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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM178A
All Species:
6.67
Human Site:
T400
Identified Species:
20.95
UniProt:
Q8IX21
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IX21
NP_060591.3
1173
131873
T400
S
K
E
P
S
D
E
T
D
G
S
S
A
G
L
Chimpanzee
Pan troglodytes
XP_001168969
1173
132024
T400
S
K
E
P
N
D
E
T
D
G
S
S
A
G
L
Rhesus Macaque
Macaca mulatta
XP_001108956
1171
132181
N398
E
D
I
S
K
E
P
N
D
E
T
D
R
S
S
Dog
Lupus familis
XP_850567
1170
131556
S398
E
D
I
S
K
E
P
S
E
E
V
D
R
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6P9P0
1278
143951
D505
G
G
V
L
R
L
E
D
I
A
K
E
P
E
D
Rat
Rattus norvegicus
NP_001128084
1134
126682
P395
L
E
D
I
A
K
E
P
D
D
E
T
D
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512094
973
110695
S247
F
L
S
I
S
N
I
S
N
Q
V
R
W
S
P
Chicken
Gallus gallus
XP_421726
750
84767
C24
E
A
D
S
Q
K
A
C
A
R
N
N
G
N
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.7
90.5
N.A.
77.7
80.6
N.A.
40.3
31.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
98
94.5
N.A.
83.4
86.3
N.A.
56.2
45
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
6.6
0
N.A.
6.6
13.3
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
20
N.A.
6.6
40
N.A.
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
0
13
0
13
0
13
13
0
0
25
0
13
% A
% Cys:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% C
% Asp:
0
25
25
0
0
25
0
13
50
13
0
25
13
0
13
% D
% Glu:
38
13
25
0
0
25
50
0
13
25
13
13
0
13
0
% E
% Phe:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
13
0
0
0
0
0
0
0
25
0
0
13
25
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
25
25
0
0
13
0
13
0
0
0
0
0
0
% I
% Lys:
0
25
0
0
25
25
0
0
0
0
13
0
0
0
0
% K
% Leu:
13
13
0
13
0
13
0
0
0
0
0
0
0
0
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
13
13
0
13
13
0
13
13
0
13
0
% N
% Pro:
0
0
0
25
0
0
25
13
0
0
0
0
13
0
13
% P
% Gln:
0
0
0
0
13
0
0
0
0
13
0
0
0
0
0
% Q
% Arg:
0
0
0
0
13
0
0
0
0
13
0
13
25
13
0
% R
% Ser:
25
0
13
38
25
0
0
25
0
0
25
25
0
38
38
% S
% Thr:
0
0
0
0
0
0
0
25
0
0
13
13
0
0
0
% T
% Val:
0
0
13
0
0
0
0
0
0
0
25
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _