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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCUBE3
All Species:
15.15
Human Site:
S406
Identified Species:
37.04
UniProt:
Q8IX30
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IX30
NP_689966.2
993
109282
S406
E
P
L
K
C
Q
G
S
P
G
A
S
K
A
M
Chimpanzee
Pan troglodytes
XP_001169046
997
109805
C411
C
S
I
N
N
G
G
C
Q
Q
V
C
V
N
T
Rhesus Macaque
Macaca mulatta
XP_001111806
1145
125389
S564
E
P
L
K
C
Q
G
S
P
G
A
S
K
A
M
Dog
Lupus familis
XP_538874
1009
111038
S422
E
P
V
K
C
Q
S
S
P
G
A
S
K
A
M
Cat
Felis silvestris
Mouse
Mus musculus
Q66PY1
993
108966
S406
E
P
V
K
C
Q
S
S
L
G
A
S
K
A
M
Rat
Rattus norvegicus
O88281
1574
165428
G422
D
V
D
E
C
A
S
G
H
G
G
C
E
H
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510365
931
103588
N352
G
C
Q
Q
I
C
V
N
T
L
G
G
Y
K
C
Chicken
Gallus gallus
O73775
704
78120
S154
E
G
T
D
V
S
I
S
D
D
A
P
K
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5G872
1010
112158
E427
W
N
K
K
D
C
I
E
A
E
D
S
P
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782645
907
100435
S355
A
T
N
D
T
L
P
S
C
S
A
S
V
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.6
81
95
N.A.
95.8
22.4
N.A.
52.1
22.3
N.A.
60.8
N.A.
N.A.
N.A.
N.A.
41.4
Protein Similarity:
100
74.4
82.7
96.7
N.A.
97.9
32.5
N.A.
65
34.2
N.A.
74.1
N.A.
N.A.
N.A.
N.A.
57.9
P-Site Identity:
100
6.6
100
86.6
N.A.
80
13.3
N.A.
0
26.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
13.3
100
93.3
N.A.
86.6
33.3
N.A.
13.3
26.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
0
10
0
60
0
0
40
0
% A
% Cys:
10
10
0
0
50
20
0
10
10
0
0
20
0
0
10
% C
% Asp:
10
0
10
20
10
0
0
0
10
10
10
0
0
10
0
% D
% Glu:
50
0
0
10
0
0
0
10
0
10
0
0
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
0
10
30
10
0
50
20
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
10
% H
% Ile:
0
0
10
0
10
0
20
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
50
0
0
0
0
0
0
0
0
50
20
0
% K
% Leu:
0
0
20
0
0
10
0
0
10
10
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
40
% M
% Asn:
0
10
10
10
10
0
0
10
0
0
0
0
0
10
0
% N
% Pro:
0
40
0
0
0
0
10
0
30
0
0
10
10
0
0
% P
% Gln:
0
0
10
10
0
40
0
0
10
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
0
10
30
60
0
10
0
60
0
0
0
% S
% Thr:
0
10
10
0
10
0
0
0
10
0
0
0
0
0
10
% T
% Val:
0
10
20
0
10
0
10
0
0
0
10
0
20
0
20
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _