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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCUBE3
All Species:
14.55
Human Site:
S590
Identified Species:
35.56
UniProt:
Q8IX30
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IX30
NP_689966.2
993
109282
S590
S
L
K
M
L
R
K
S
I
N
Q
D
R
F
L
Chimpanzee
Pan troglodytes
XP_001169046
997
109805
A592
A
I
R
T
L
R
K
A
V
H
R
E
Q
F
H
Rhesus Macaque
Macaca mulatta
XP_001111806
1145
125389
D746
L
R
K
S
I
N
Q
D
R
F
L
L
R
L
A
Dog
Lupus familis
XP_538874
1009
111038
S606
S
L
K
M
L
R
K
S
I
N
Q
D
R
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q66PY1
993
108966
S590
S
L
K
M
L
R
K
S
I
N
Q
D
R
F
L
Rat
Rattus norvegicus
O88281
1574
165428
T845
N
D
G
H
C
D
P
T
T
G
R
C
S
C
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510365
931
103588
E531
L
R
K
T
I
H
R
E
Q
L
F
L
R
F
S
Chicken
Gallus gallus
O73775
704
78120
Y333
C
I
N
T
D
G
S
Y
T
C
Q
R
I
S
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5G872
1010
112158
S609
T
I
R
T
L
R
K
S
I
N
R
E
Q
F
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782645
907
100435
C534
D
A
G
R
C
V
A
C
S
M
G
T
Y
Y
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.6
81
95
N.A.
95.8
22.4
N.A.
52.1
22.3
N.A.
60.8
N.A.
N.A.
N.A.
N.A.
41.4
Protein Similarity:
100
74.4
82.7
96.7
N.A.
97.9
32.5
N.A.
65
34.2
N.A.
74.1
N.A.
N.A.
N.A.
N.A.
57.9
P-Site Identity:
100
26.6
13.3
100
N.A.
100
0
N.A.
20
6.6
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
86.6
26.6
100
N.A.
100
20
N.A.
33.3
13.3
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
10
10
0
0
0
0
0
0
20
% A
% Cys:
10
0
0
0
20
0
0
10
0
10
0
10
0
10
0
% C
% Asp:
10
10
0
0
10
10
0
10
0
0
0
30
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
0
0
0
20
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
10
0
0
60
0
% F
% Gly:
0
0
20
0
0
10
0
0
0
10
10
0
0
0
0
% G
% His:
0
0
0
10
0
10
0
0
0
10
0
0
0
0
30
% H
% Ile:
0
30
0
0
20
0
0
0
40
0
0
0
10
0
0
% I
% Lys:
0
0
50
0
0
0
50
0
0
0
0
0
0
0
0
% K
% Leu:
20
30
0
0
50
0
0
0
0
10
10
20
0
10
30
% L
% Met:
0
0
0
30
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
10
0
10
0
0
10
0
0
0
40
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
10
0
10
0
40
0
20
0
0
% Q
% Arg:
0
20
20
10
0
50
10
0
10
0
30
10
50
0
0
% R
% Ser:
30
0
0
10
0
0
10
40
10
0
0
0
10
10
10
% S
% Thr:
10
0
0
40
0
0
0
10
20
0
0
10
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _