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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCUBE3
All Species:
9.7
Human Site:
T541
Identified Species:
23.7
UniProt:
Q8IX30
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IX30
NP_689966.2
993
109282
T541
G
K
G
R
R
A
R
T
P
P
G
K
E
V
T
Chimpanzee
Pan troglodytes
XP_001169046
997
109805
P544
V
P
G
A
P
G
R
P
S
T
P
K
E
M
F
Rhesus Macaque
Macaca mulatta
XP_001111806
1145
125389
V699
R
T
P
P
G
K
E
V
T
R
L
T
L
E
L
Dog
Lupus familis
XP_538874
1009
111038
T557
G
K
G
R
R
A
R
T
P
P
G
K
E
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q66PY1
993
108966
T541
G
K
G
R
R
A
R
T
P
P
G
K
E
V
T
Rat
Rattus norvegicus
O88281
1574
165428
G725
C
R
T
Q
C
P
P
G
Y
Q
G
E
D
C
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510365
931
103588
E484
D
R
T
T
S
S
K
E
M
F
I
T
V
D
F
Chicken
Gallus gallus
O73775
704
78120
S286
I
C
Q
N
T
P
G
S
F
R
C
R
P
K
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5G872
1010
112158
K559
Q
R
S
R
H
G
R
K
A
G
E
E
E
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782645
907
100435
K487
R
L
I
T
K
L
R
K
A
I
E
R
D
H
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.6
81
95
N.A.
95.8
22.4
N.A.
52.1
22.3
N.A.
60.8
N.A.
N.A.
N.A.
N.A.
41.4
Protein Similarity:
100
74.4
82.7
96.7
N.A.
97.9
32.5
N.A.
65
34.2
N.A.
74.1
N.A.
N.A.
N.A.
N.A.
57.9
P-Site Identity:
100
26.6
0
100
N.A.
100
6.6
N.A.
0
0
N.A.
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
33.3
0
100
N.A.
100
33.3
N.A.
20
13.3
N.A.
40
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
30
0
0
20
0
0
0
0
0
0
% A
% Cys:
10
10
0
0
10
0
0
0
0
0
10
0
0
10
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
0
20
10
0
% D
% Glu:
0
0
0
0
0
0
10
10
0
0
20
20
50
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
30
% F
% Gly:
30
0
40
0
10
20
10
10
0
10
40
0
0
10
10
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
10
0
10
0
0
0
0
0
0
10
10
0
0
0
0
% I
% Lys:
0
30
0
0
10
10
10
20
0
0
0
40
0
10
0
% K
% Leu:
0
10
0
0
0
10
0
0
0
0
10
0
10
0
20
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
10
10
10
20
10
10
30
30
10
0
10
0
0
% P
% Gln:
10
0
10
10
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
20
30
0
40
30
0
60
0
0
20
0
20
0
0
0
% R
% Ser:
0
0
10
0
10
10
0
10
10
0
0
0
0
0
10
% S
% Thr:
0
10
20
20
10
0
0
30
10
10
0
20
0
0
30
% T
% Val:
10
0
0
0
0
0
0
10
0
0
0
0
10
30
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _