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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPAS3
All Species:
13.64
Human Site:
S237
Identified Species:
25
UniProt:
Q8IXF0
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXF0
NP_071406.1
933
100805
S237
A
S
S
A
S
S
S
S
Q
S
E
T
P
E
P
Chimpanzee
Pan troglodytes
A2T6X9
766
85495
G113
E
T
A
S
V
H
L
G
L
S
Q
V
E
L
T
Rhesus Macaque
Macaca mulatta
XP_001108628
965
103732
S273
A
S
S
A
S
S
S
S
Q
S
E
T
P
E
P
Dog
Lupus familis
XP_541539
594
63373
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZQ0
925
100440
S242
A
S
S
A
S
S
S
S
Q
S
E
T
P
E
P
Rat
Rattus norvegicus
O35800
825
92301
K172
R
S
F
F
L
R
M
K
C
T
L
T
S
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512327
625
68790
Chicken
Gallus gallus
Q9YIB9
811
90524
G158
R
N
G
P
V
K
K
G
K
E
Q
N
T
E
R
Frog
Xenopus laevis
Q9I8A9
805
90946
R151
L
R
E
M
L
T
F
R
N
G
P
A
K
K
R
Zebra Danio
Brachydanio rerio
Q98SJ5
745
82716
I92
L
Q
T
L
D
G
F
I
F
V
V
A
P
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24119
995
106459
G323
G
S
S
S
S
G
G
G
G
G
G
A
G
G
G
Honey Bee
Apis mellifera
XP_391937
963
103825
S298
A
S
E
E
H
G
S
S
S
T
A
N
P
D
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783845
933
103039
S247
D
G
N
S
T
S
G
S
G
A
G
S
P
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.1
94.7
35.1
N.A.
94
24.2
N.A.
64.1
24.5
20.2
27.4
N.A.
32.4
31
N.A.
33.1
Protein Similarity:
100
40.2
94.9
45.2
N.A.
95.3
41.7
N.A.
64.7
40.2
38.5
41.9
N.A.
46.7
47.4
N.A.
49.3
P-Site Identity:
100
6.6
100
0
N.A.
100
13.3
N.A.
0
6.6
0
6.6
N.A.
20
33.3
N.A.
20
P-Site Similarity:
100
33.3
100
0
N.A.
100
20
N.A.
0
26.6
13.3
20
N.A.
26.6
46.6
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
0
8
24
0
0
0
0
0
8
8
24
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
0
0
0
0
0
0
0
0
16
0
% D
% Glu:
8
0
16
8
0
0
0
0
0
8
24
0
8
31
0
% E
% Phe:
0
0
8
8
0
0
16
0
8
0
0
0
0
0
0
% F
% Gly:
8
8
8
0
0
24
16
24
16
16
16
0
8
8
24
% G
% His:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
8
8
8
8
0
0
0
8
8
0
% K
% Leu:
16
0
0
8
16
0
8
0
8
0
8
0
0
8
0
% L
% Met:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
0
0
0
0
8
0
0
16
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
8
0
47
0
24
% P
% Gln:
0
8
0
0
0
0
0
0
24
0
16
0
0
0
0
% Q
% Arg:
16
8
0
0
0
8
0
8
0
0
0
0
0
8
16
% R
% Ser:
0
47
31
24
31
31
31
39
8
31
0
8
8
0
0
% S
% Thr:
0
8
8
0
8
8
0
0
0
16
0
31
8
0
8
% T
% Val:
0
0
0
0
16
0
0
0
0
8
8
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _