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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NPAS3 All Species: 13.94
Human Site: S299 Identified Species: 25.56
UniProt: Q8IXF0 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IXF0 NP_071406.1 933 100805 S299 L R L R V S L S H G R T V P S
Chimpanzee Pan troglodytes A2T6X9 766 85495 L175 L A K R N A G L T C G G Y K V
Rhesus Macaque Macaca mulatta XP_001108628 965 103732 S335 L R L R V S L S H G R T V P S
Dog Lupus familis XP_541539 594 63373
Cat Felis silvestris
Mouse Mus musculus Q9QZQ0 925 100440 S304 L R L R V P L S H G R T V P S
Rat Rattus norvegicus O35800 825 92301 E234 I P H P S N I E I P L D S K T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512327 625 68790 Y34 G I Y C E S T Y Q N L Q A L R
Chicken Gallus gallus Q9YIB9 811 90524 L220 K K P P M T C L V L I C E P I
Frog Xenopus laevis Q9I8A9 805 90946 Y213 N N Q N H C G Y K K P P M T C
Zebra Danio Brachydanio rerio Q98SJ5 745 82716 Y154 H S H F V H E Y E M E R S F F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24119 995 106459 C385 S T L T K R G C H F K S S G Y
Honey Bee Apis mellifera XP_391937 963 103825 S360 L R P Q Y T F S H T R K S A P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783845 933 103039 S309 L R P E L S L S Q Y N H H P P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.1 94.7 35.1 N.A. 94 24.2 N.A. 64.1 24.5 20.2 27.4 N.A. 32.4 31 N.A. 33.1
Protein Similarity: 100 40.2 94.9 45.2 N.A. 95.3 41.7 N.A. 64.7 40.2 38.5 41.9 N.A. 46.7 47.4 N.A. 49.3
P-Site Identity: 100 13.3 100 0 N.A. 93.3 0 N.A. 6.6 6.6 0 6.6 N.A. 13.3 33.3 N.A. 40
P-Site Similarity: 100 20 100 0 N.A. 93.3 26.6 N.A. 6.6 26.6 6.6 6.6 N.A. 26.6 46.6 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 8 0 0 0 0 0 0 8 8 0 % A
% Cys: 0 0 0 8 0 8 8 8 0 8 0 8 0 0 8 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % D
% Glu: 0 0 0 8 8 0 8 8 8 0 8 0 8 0 0 % E
% Phe: 0 0 0 8 0 0 8 0 0 8 0 0 0 8 8 % F
% Gly: 8 0 0 0 0 0 24 0 0 24 8 8 0 8 0 % G
% His: 8 0 16 0 8 8 0 0 39 0 0 8 8 0 0 % H
% Ile: 8 8 0 0 0 0 8 0 8 0 8 0 0 0 8 % I
% Lys: 8 8 8 0 8 0 0 0 8 8 8 8 0 16 0 % K
% Leu: 47 0 31 0 8 0 31 16 0 8 16 0 0 8 0 % L
% Met: 0 0 0 0 8 0 0 0 0 8 0 0 8 0 0 % M
% Asn: 8 8 0 8 8 8 0 0 0 8 8 0 0 0 0 % N
% Pro: 0 8 24 16 0 8 0 0 0 8 8 8 0 39 16 % P
% Gln: 0 0 8 8 0 0 0 0 16 0 0 8 0 0 0 % Q
% Arg: 0 39 0 31 0 8 0 0 0 0 31 8 0 0 8 % R
% Ser: 8 8 0 0 8 31 0 39 0 0 0 8 31 0 24 % S
% Thr: 0 8 0 8 0 16 8 0 8 8 0 24 0 8 8 % T
% Val: 0 0 0 0 31 0 0 0 8 0 0 0 24 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 8 0 0 24 0 8 0 0 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _