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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPAS3
All Species:
17.27
Human Site:
S381
Identified Species:
31.67
UniProt:
Q8IXF0
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXF0
NP_071406.1
933
100805
S381
D
V
E
G
I
R
H
S
H
L
D
L
L
N
K
Chimpanzee
Pan troglodytes
A2T6X9
766
85495
E256
V
A
E
L
T
G
Y
E
P
Q
D
L
I
E
K
Rhesus Macaque
Macaca mulatta
XP_001108628
965
103732
S417
D
V
E
G
I
R
H
S
H
L
D
L
L
N
K
Dog
Lupus familis
XP_541539
594
63373
D84
G
A
I
S
S
Q
L
D
K
A
S
I
V
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZQ0
925
100440
S386
D
V
E
G
I
R
H
S
H
L
D
L
L
N
K
Rat
Rattus norvegicus
O35800
825
92301
V315
L
A
K
R
G
G
Y
V
W
V
E
T
Q
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512327
625
68790
S115
E
G
P
P
P
N
T
S
V
K
G
A
Q
R
R
Chicken
Gallus gallus
Q9YIB9
811
90524
T301
M
F
T
K
G
Q
V
T
T
G
Q
Y
R
M
L
Frog
Xenopus laevis
Q9I8A9
805
90946
N294
H
L
T
K
P
N
Y
N
M
F
T
K
G
Q
V
Zebra Danio
Brachydanio rerio
Q98SJ5
745
82716
R235
H
S
N
M
F
M
F
R
A
S
L
D
M
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24119
995
106459
E468
D
L
L
D
Y
S
P
E
D
L
V
N
K
S
L
Honey Bee
Apis mellifera
XP_391937
963
103825
S442
D
A
N
R
L
R
K
S
H
I
D
L
I
H
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783845
933
103039
S391
D
I
A
N
V
R
T
S
H
Q
D
L
L
N
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.1
94.7
35.1
N.A.
94
24.2
N.A.
64.1
24.5
20.2
27.4
N.A.
32.4
31
N.A.
33.1
Protein Similarity:
100
40.2
94.9
45.2
N.A.
95.3
41.7
N.A.
64.7
40.2
38.5
41.9
N.A.
46.7
47.4
N.A.
49.3
P-Site Identity:
100
26.6
100
0
N.A.
100
0
N.A.
6.6
0
0
0
N.A.
13.3
46.6
N.A.
60
P-Site Similarity:
100
40
100
20
N.A.
100
26.6
N.A.
20
13.3
20
6.6
N.A.
26.6
73.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
31
8
0
0
0
0
0
8
8
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
47
0
0
8
0
0
0
8
8
0
47
8
0
0
0
% D
% Glu:
8
0
31
0
0
0
0
16
0
0
8
0
0
8
0
% E
% Phe:
0
8
0
0
8
0
8
0
0
8
0
0
0
0
0
% F
% Gly:
8
8
0
24
16
16
0
0
0
8
8
0
8
0
0
% G
% His:
16
0
0
0
0
0
24
0
39
0
0
0
0
8
0
% H
% Ile:
0
8
8
0
24
0
0
0
0
8
0
8
16
0
0
% I
% Lys:
0
0
8
16
0
0
8
0
8
8
0
8
8
8
47
% K
% Leu:
8
16
8
8
8
0
8
0
0
31
8
47
31
0
31
% L
% Met:
8
0
0
8
0
8
0
0
8
0
0
0
8
8
0
% M
% Asn:
0
0
16
8
0
16
0
8
0
0
0
8
0
31
0
% N
% Pro:
0
0
8
8
16
0
8
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
16
0
0
0
16
8
0
16
8
0
% Q
% Arg:
0
0
0
16
0
39
0
8
0
0
0
0
8
16
8
% R
% Ser:
0
8
0
8
8
8
0
47
0
8
8
0
0
8
0
% S
% Thr:
0
0
16
0
8
0
16
8
8
0
8
8
0
0
8
% T
% Val:
8
24
0
0
8
0
8
8
8
8
8
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
24
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _