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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NPAS3 All Species: 18.79
Human Site: S493 Identified Species: 34.44
UniProt: Q8IXF0 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IXF0 NP_071406.1 933 100805 S493 K G N Q S E N S E D P E P D R
Chimpanzee Pan troglodytes A2T6X9 766 85495 T365 S S S T P T M T D N R K G A K
Rhesus Macaque Macaca mulatta XP_001108628 965 103732 S529 K G N Q S E N S E D P E P D R
Dog Lupus familis XP_541539 594 63373 S193 Y I H P G D H S E V L E Q L G
Cat Felis silvestris
Mouse Mus musculus Q9QZQ0 925 100440 S498 K G N Q S E N S E D P E P D R
Rat Rattus norvegicus O35800 825 92301 Q424 D T E T E D Q Q L E D V P L Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512327 625 68790 S224 A S S A S S S S Q S E T P E P
Chicken Gallus gallus Q9YIB9 811 90524 S410 A A G D T I I S L D F S S N E
Frog Xenopus laevis Q9I8A9 805 90946 A403 P E S L T V L A P D A G D E I
Zebra Danio Brachydanio rerio Q98SJ5 745 82716 L344 Y K G L Q L S L D Q A A S T K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24119 995 106459 S578 G N D K S S G S P G G D A S G
Honey Bee Apis mellifera XP_391937 963 103825 R554 Q H Q E H P H R S P P E D R E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783845 933 103039 S502 Q V G T G G D S N N N S K G H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.1 94.7 35.1 N.A. 94 24.2 N.A. 64.1 24.5 20.2 27.4 N.A. 32.4 31 N.A. 33.1
Protein Similarity: 100 40.2 94.9 45.2 N.A. 95.3 41.7 N.A. 64.7 40.2 38.5 41.9 N.A. 46.7 47.4 N.A. 49.3
P-Site Identity: 100 0 100 20 N.A. 100 6.6 N.A. 20 13.3 6.6 0 N.A. 13.3 13.3 N.A. 6.6
P-Site Similarity: 100 40 100 40 N.A. 100 20 N.A. 46.6 26.6 33.3 20 N.A. 33.3 33.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 8 0 8 0 0 0 8 0 0 16 8 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 8 8 0 16 8 0 16 39 8 8 16 24 0 % D
% Glu: 0 8 8 8 8 24 0 0 31 8 8 39 0 16 16 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 8 24 24 0 16 8 8 0 0 8 8 8 8 8 16 % G
% His: 0 8 8 0 8 0 16 0 0 0 0 0 0 0 8 % H
% Ile: 0 8 0 0 0 8 8 0 0 0 0 0 0 0 8 % I
% Lys: 24 8 0 8 0 0 0 0 0 0 0 8 8 0 16 % K
% Leu: 0 0 0 16 0 8 8 8 16 0 8 0 0 16 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 24 0 0 0 24 0 8 16 8 0 0 8 0 % N
% Pro: 8 0 0 8 8 8 0 0 16 8 31 0 39 0 8 % P
% Gln: 16 0 8 24 8 0 8 8 8 8 0 0 8 0 0 % Q
% Arg: 0 0 0 0 0 0 0 8 0 0 8 0 0 8 24 % R
% Ser: 8 16 24 0 39 16 16 62 8 8 0 16 16 8 0 % S
% Thr: 0 8 0 24 16 8 0 8 0 0 0 8 0 8 0 % T
% Val: 0 8 0 0 0 8 0 0 0 8 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 16 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _