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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPAS3
All Species:
12.42
Human Site:
S519
Identified Species:
22.78
UniProt:
Q8IXF0
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXF0
NP_071406.1
933
100805
S519
N
C
N
D
D
G
H
S
S
S
N
P
D
S
R
Chimpanzee
Pan troglodytes
A2T6X9
766
85495
Y390
R
T
S
P
Y
P
Q
Y
S
G
F
H
T
E
R
Rhesus Macaque
Macaca mulatta
XP_001108628
965
103732
S555
N
C
N
D
D
G
H
S
S
S
N
P
D
S
R
Dog
Lupus familis
XP_541539
594
63373
S218
P
P
S
V
P
S
S
S
S
S
S
S
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZQ0
925
100440
S524
N
C
N
D
D
G
H
S
S
S
N
P
D
S
R
Rat
Rattus norvegicus
O35800
825
92301
M449
K
L
N
I
N
L
A
M
S
P
L
P
A
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512327
625
68790
S249
T
D
N
T
L
E
R
S
F
F
I
R
M
K
S
Chicken
Gallus gallus
Q9YIB9
811
90524
P435
L
Y
N
D
V
M
L
P
S
S
S
E
K
L
Q
Frog
Xenopus laevis
Q9I8A9
805
90946
L429
K
P
Y
E
D
V
P
L
Y
N
D
V
M
L
H
Zebra Danio
Brachydanio rerio
Q98SJ5
745
82716
V369
P
V
T
E
N
R
R
V
G
K
S
R
V
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24119
995
106459
D604
K
L
N
S
P
K
T
D
S
E
G
H
S
H
R
Honey Bee
Apis mellifera
XP_391937
963
103825
A580
S
R
H
H
D
S
I
A
Q
L
Q
Q
E
P
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783845
933
103039
Q536
S
K
K
H
R
G
A
Q
I
T
R
N
E
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.1
94.7
35.1
N.A.
94
24.2
N.A.
64.1
24.5
20.2
27.4
N.A.
32.4
31
N.A.
33.1
Protein Similarity:
100
40.2
94.9
45.2
N.A.
95.3
41.7
N.A.
64.7
40.2
38.5
41.9
N.A.
46.7
47.4
N.A.
49.3
P-Site Identity:
100
13.3
100
26.6
N.A.
100
26.6
N.A.
13.3
26.6
6.6
13.3
N.A.
20
6.6
N.A.
6.6
P-Site Similarity:
100
20
100
40
N.A.
100
33.3
N.A.
13.3
40
26.6
33.3
N.A.
20
40
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
16
8
0
0
0
0
8
0
0
% A
% Cys:
0
24
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
31
39
0
0
8
0
0
8
0
24
0
0
% D
% Glu:
0
0
0
16
0
8
0
0
0
8
0
8
16
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
8
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
31
0
0
8
8
8
0
0
0
0
% G
% His:
0
0
8
16
0
0
24
0
0
0
0
16
0
8
8
% H
% Ile:
0
0
0
8
0
0
8
0
8
0
8
0
0
0
0
% I
% Lys:
24
8
8
0
0
8
0
0
0
8
0
0
8
8
0
% K
% Leu:
8
16
0
0
8
8
8
8
0
8
8
0
0
16
0
% L
% Met:
0
0
0
0
0
8
0
8
0
0
0
0
16
0
0
% M
% Asn:
24
0
54
0
16
0
0
0
0
8
24
8
0
0
0
% N
% Pro:
16
16
0
8
16
8
8
8
0
8
0
31
0
16
0
% P
% Gln:
0
0
0
0
0
0
8
8
8
0
8
8
0
0
16
% Q
% Arg:
8
8
0
0
8
8
16
0
0
0
8
16
0
0
47
% R
% Ser:
16
0
16
8
0
16
8
39
62
39
24
8
16
47
16
% S
% Thr:
8
8
8
8
0
0
8
0
0
8
0
0
8
0
8
% T
% Val:
0
8
0
8
8
8
0
8
0
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
8
0
0
8
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _