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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NPAS3 All Species: 13.33
Human Site: S525 Identified Species: 24.44
UniProt: Q8IXF0 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IXF0 NP_071406.1 933 100805 S525 H S S S N P D S R D S D D S F
Chimpanzee Pan troglodytes A2T6X9 766 85495 E396 Q Y S G F H T E R S E S D H D
Rhesus Macaque Macaca mulatta XP_001108628 965 103732 S561 H S S S N P D S R D S D D S F
Dog Lupus familis XP_541539 594 63373 S224 S S S S S S S S S L A D T P E
Cat Felis silvestris
Mouse Mus musculus Q9QZQ0 925 100440 S530 H S S S N P D S R D S D D S F
Rat Rattus norvegicus O35800 825 92301 S455 A M S P L P A S E T P K P L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512327 625 68790 K255 R S F F I R M K S T L T K R G
Chicken Gallus gallus Q9YIB9 811 90524 L441 L P S S S E K L Q N I N I A M
Frog Xenopus laevis Q9I8A9 805 90946 L435 P L Y N D V M L H S T S N K L
Zebra Danio Brachydanio rerio Q98SJ5 745 82716 S375 R V G K S R V S R T K T K T R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24119 995 106459 H610 T D S E G H S H R G R G R S A
Honey Bee Apis mellifera XP_391937 963 103825 P586 I A Q L Q Q E P Q T A V G N I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783845 933 103039 P542 A Q I T R N E P T G N H G N L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.1 94.7 35.1 N.A. 94 24.2 N.A. 64.1 24.5 20.2 27.4 N.A. 32.4 31 N.A. 33.1
Protein Similarity: 100 40.2 94.9 45.2 N.A. 95.3 41.7 N.A. 64.7 40.2 38.5 41.9 N.A. 46.7 47.4 N.A. 49.3
P-Site Identity: 100 20 100 33.3 N.A. 100 20 N.A. 6.6 13.3 0 13.3 N.A. 20 0 N.A. 0
P-Site Similarity: 100 20 100 46.6 N.A. 100 20 N.A. 6.6 46.6 26.6 26.6 N.A. 20 33.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 8 0 0 0 0 8 0 0 0 16 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 8 0 24 0 0 24 0 31 31 0 8 % D
% Glu: 0 0 0 8 0 8 16 8 8 0 8 0 0 0 8 % E
% Phe: 0 0 8 8 8 0 0 0 0 0 0 0 0 0 24 % F
% Gly: 0 0 8 8 8 0 0 0 0 16 0 8 16 0 8 % G
% His: 24 0 0 0 0 16 0 8 8 0 0 8 0 8 0 % H
% Ile: 8 0 8 0 8 0 0 0 0 0 8 0 8 0 8 % I
% Lys: 0 0 0 8 0 0 8 8 0 0 8 8 16 8 0 % K
% Leu: 8 8 0 8 8 0 0 16 0 8 8 0 0 8 16 % L
% Met: 0 8 0 0 0 0 16 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 8 24 8 0 0 0 8 8 8 8 16 0 % N
% Pro: 8 8 0 8 0 31 0 16 0 0 8 0 8 8 0 % P
% Gln: 8 8 8 0 8 8 0 0 16 0 0 0 0 0 0 % Q
% Arg: 16 0 0 0 8 16 0 0 47 0 8 0 8 8 16 % R
% Ser: 8 39 62 39 24 8 16 47 16 16 24 16 0 31 0 % S
% Thr: 8 0 0 8 0 0 8 0 8 31 8 16 8 8 0 % T
% Val: 0 8 0 0 0 8 8 0 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _