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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPAS3
All Species:
11.21
Human Site:
S531
Identified Species:
20.56
UniProt:
Q8IXF0
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXF0
NP_071406.1
933
100805
S531
D
S
R
D
S
D
D
S
F
E
H
S
D
F
E
Chimpanzee
Pan troglodytes
A2T6X9
766
85495
H402
T
E
R
S
E
S
D
H
D
S
Q
W
G
G
S
Rhesus Macaque
Macaca mulatta
XP_001108628
965
103732
S567
D
S
R
D
S
D
D
S
F
E
H
S
D
F
E
Dog
Lupus familis
XP_541539
594
63373
P230
S
S
S
L
A
D
T
P
E
I
E
A
S
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZQ0
925
100440
S536
D
S
R
D
S
D
D
S
F
E
H
S
D
F
E
Rat
Rattus norvegicus
O35800
825
92301
L461
A
S
E
T
P
K
P
L
R
S
S
A
D
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512327
625
68790
R261
M
K
S
T
L
T
K
R
G
V
H
I
K
S
S
Chicken
Gallus gallus
Q9YIB9
811
90524
A447
K
L
Q
N
I
N
I
A
M
S
P
L
P
A
S
Frog
Xenopus laevis
Q9I8A9
805
90946
K441
M
L
H
S
T
S
N
K
L
E
S
T
P
I
T
Zebra Danio
Brachydanio rerio
Q98SJ5
745
82716
T381
V
S
R
T
K
T
K
T
R
L
S
P
Y
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24119
995
106459
S616
S
H
R
G
R
G
R
S
A
A
A
S
H
G
S
Honey Bee
Apis mellifera
XP_391937
963
103825
N592
E
P
Q
T
A
V
G
N
I
S
T
L
V
V
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783845
933
103039
N548
E
P
T
G
N
H
G
N
L
E
H
K
S
E
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.1
94.7
35.1
N.A.
94
24.2
N.A.
64.1
24.5
20.2
27.4
N.A.
32.4
31
N.A.
33.1
Protein Similarity:
100
40.2
94.9
45.2
N.A.
95.3
41.7
N.A.
64.7
40.2
38.5
41.9
N.A.
46.7
47.4
N.A.
49.3
P-Site Identity:
100
13.3
100
13.3
N.A.
100
13.3
N.A.
6.6
0
6.6
13.3
N.A.
20
0
N.A.
13.3
P-Site Similarity:
100
13.3
100
26.6
N.A.
100
20
N.A.
6.6
26.6
26.6
26.6
N.A.
20
33.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
16
0
0
8
8
8
8
16
0
16
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
0
0
24
0
31
31
0
8
0
0
0
31
0
0
% D
% Glu:
16
8
8
0
8
0
0
0
8
39
8
0
0
8
24
% E
% Phe:
0
0
0
0
0
0
0
0
24
0
0
0
0
24
0
% F
% Gly:
0
0
0
16
0
8
16
0
8
0
0
0
8
16
0
% G
% His:
0
8
8
0
0
8
0
8
0
0
39
0
8
0
0
% H
% Ile:
0
0
0
0
8
0
8
0
8
8
0
8
0
8
0
% I
% Lys:
8
8
0
0
8
8
16
8
0
0
0
8
8
0
8
% K
% Leu:
0
16
0
8
8
0
0
8
16
8
0
16
0
0
0
% L
% Met:
16
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% M
% Asn:
0
0
0
8
8
8
8
16
0
0
0
0
0
0
0
% N
% Pro:
0
16
0
0
8
0
8
8
0
0
8
8
16
8
0
% P
% Gln:
0
0
16
0
0
0
0
0
0
0
8
0
0
0
8
% Q
% Arg:
0
0
47
0
8
0
8
8
16
0
0
0
0
0
0
% R
% Ser:
16
47
16
16
24
16
0
31
0
31
24
31
16
16
31
% S
% Thr:
8
0
8
31
8
16
8
8
0
0
8
8
0
0
8
% T
% Val:
8
0
0
0
0
8
0
0
0
8
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _