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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NPAS3 All Species: 4.55
Human Site: S565 Identified Species: 8.33
UniProt: Q8IXF0 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IXF0 NP_071406.1 933 100805 S565 E R Y V E S E S D L R L Q N C
Chimpanzee Pan troglodytes A2T6X9 766 85495 P426 L L D P A D R P G S Q H D A S
Rhesus Macaque Macaca mulatta XP_001108628 965 103732 S601 E R Y V E S E S D L R L Q N C
Dog Lupus familis XP_541539 594 63373 M254 E R S F F I R M K S T L T K R
Cat Felis silvestris
Mouse Mus musculus Q9QZQ0 925 100440 A570 E R Y V E S E A D L R L Q P C
Rat Rattus norvegicus O35800 825 92301 G485 E S S P E S L G L S F T M P Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512327 625 68790 L285 R L R L R V S L S H G R T V P
Chicken Gallus gallus Q9YIB9 811 90524 E471 A D P A L N R E V V S K L E P
Frog Xenopus laevis Q9I8A9 805 90946 P465 P L R S N V D P A L N R E V V
Zebra Danio Brachydanio rerio Q98SJ5 745 82716 W405 E S D Q D S P W G G S P L T D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24119 995 106459 V640 D S P T P L G V E I D S G V L
Honey Bee Apis mellifera XP_391937 963 103825 E616 E D D S S S N E E E D E E D D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783845 933 103039 D578 Q K P K P C P D V I P K Q V I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.1 94.7 35.1 N.A. 94 24.2 N.A. 64.1 24.5 20.2 27.4 N.A. 32.4 31 N.A. 33.1
Protein Similarity: 100 40.2 94.9 45.2 N.A. 95.3 41.7 N.A. 64.7 40.2 38.5 41.9 N.A. 46.7 47.4 N.A. 49.3
P-Site Identity: 100 0 100 20 N.A. 86.6 20 N.A. 0 0 6.6 13.3 N.A. 0 13.3 N.A. 6.6
P-Site Similarity: 100 6.6 100 20 N.A. 93.3 20 N.A. 6.6 13.3 20 20 N.A. 20 33.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 8 0 0 8 8 0 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 24 % C
% Asp: 8 16 24 0 8 8 8 8 24 0 16 0 8 8 16 % D
% Glu: 54 0 0 0 31 0 24 16 16 8 0 8 16 8 0 % E
% Phe: 0 0 0 8 8 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 8 8 16 8 8 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 16 0 0 0 0 8 % I
% Lys: 0 8 0 8 0 0 0 0 8 0 0 16 0 8 0 % K
% Leu: 8 24 0 8 8 8 8 8 8 31 0 31 16 0 8 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 8 8 8 0 0 0 8 0 0 16 0 % N
% Pro: 8 0 24 16 16 0 16 16 0 0 8 8 0 16 16 % P
% Gln: 8 0 0 8 0 0 0 0 0 0 8 0 31 0 8 % Q
% Arg: 8 31 16 0 8 0 24 0 0 0 24 16 0 0 8 % R
% Ser: 0 24 16 16 8 47 8 16 8 24 16 8 0 0 8 % S
% Thr: 0 0 0 8 0 0 0 0 0 0 8 8 16 8 0 % T
% Val: 0 0 0 24 0 16 0 8 16 8 0 0 0 31 8 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 24 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _