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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPAS3
All Species:
11.21
Human Site:
S622
Identified Species:
20.56
UniProt:
Q8IXF0
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXF0
NP_071406.1
933
100805
S622
R
R
L
S
S
A
S
S
P
G
G
L
D
A
G
Chimpanzee
Pan troglodytes
A2T6X9
766
85495
P482
G
R
Y
F
L
G
T
P
Q
A
G
R
E
P
W
Rhesus Macaque
Macaca mulatta
XP_001108628
965
103732
S658
R
R
L
S
S
A
S
S
P
G
G
L
D
A
G
Dog
Lupus familis
XP_541539
594
63373
F310
L
H
G
H
M
I
V
F
R
L
S
L
G
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZQ0
925
100440
S627
R
R
L
S
S
A
S
S
P
G
L
D
A
G
L
Rat
Rattus norvegicus
O35800
825
92301
E541
L
V
E
K
L
F
A
E
D
T
E
A
K
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512327
625
68790
M341
E
N
R
I
S
D
Y
M
D
L
T
P
V
D
I
Chicken
Gallus gallus
Q9YIB9
811
90524
N527
D
V
D
N
D
M
A
N
E
F
K
L
E
L
V
Frog
Xenopus laevis
Q9I8A9
805
90946
S521
E
Y
C
F
D
V
D
S
E
M
A
S
E
F
K
Zebra Danio
Brachydanio rerio
Q98SJ5
745
82716
H461
N
E
L
Y
S
H
P
H
S
E
S
C
E
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24119
995
106459
T696
Q
P
L
P
K
L
P
T
M
E
Q
R
D
Q
Q
Honey Bee
Apis mellifera
XP_391937
963
103825
S672
D
R
T
S
N
A
D
S
T
G
T
S
V
K
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783845
933
103039
A642
G
M
H
H
S
P
T
A
I
S
P
I
N
H
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.1
94.7
35.1
N.A.
94
24.2
N.A.
64.1
24.5
20.2
27.4
N.A.
32.4
31
N.A.
33.1
Protein Similarity:
100
40.2
94.9
45.2
N.A.
95.3
41.7
N.A.
64.7
40.2
38.5
41.9
N.A.
46.7
47.4
N.A.
49.3
P-Site Identity:
100
13.3
100
6.6
N.A.
66.6
0
N.A.
6.6
6.6
6.6
20
N.A.
13.3
33.3
N.A.
6.6
P-Site Similarity:
100
26.6
100
6.6
N.A.
66.6
6.6
N.A.
6.6
33.3
13.3
26.6
N.A.
26.6
40
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
31
16
8
0
8
8
8
8
16
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
16
0
8
0
16
8
16
0
16
0
0
8
24
8
8
% D
% Glu:
16
8
8
0
0
0
0
8
16
16
8
0
31
0
0
% E
% Phe:
0
0
0
16
0
8
0
8
0
8
0
0
0
8
0
% F
% Gly:
16
0
8
0
0
8
0
0
0
31
24
0
8
8
24
% G
% His:
0
8
8
16
0
8
0
8
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
8
0
8
0
0
8
0
0
8
0
0
8
% I
% Lys:
0
0
0
8
8
0
0
0
0
0
8
0
8
8
8
% K
% Leu:
16
0
39
0
16
8
0
0
0
16
8
31
0
16
8
% L
% Met:
0
8
0
0
8
8
0
8
8
8
0
0
0
0
8
% M
% Asn:
8
8
0
8
8
0
0
8
0
0
0
0
8
8
0
% N
% Pro:
0
8
0
8
0
8
16
8
24
0
8
8
0
8
8
% P
% Gln:
8
0
0
0
0
0
0
0
8
0
8
0
0
8
8
% Q
% Arg:
24
39
8
0
0
0
0
0
8
0
0
16
0
8
0
% R
% Ser:
0
0
0
31
47
0
24
39
8
8
16
16
0
0
0
% S
% Thr:
0
0
8
0
0
0
16
8
8
8
16
0
0
0
8
% T
% Val:
0
16
0
0
0
8
8
0
0
0
0
0
16
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
8
8
8
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _