KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPAS3
All Species:
10.3
Human Site:
S678
Identified Species:
18.89
UniProt:
Q8IXF0
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXF0
NP_071406.1
933
100805
S678
R
E
I
S
R
N
E
S
P
Y
S
M
T
K
P
Chimpanzee
Pan troglodytes
A2T6X9
766
85495
P537
E
D
S
V
V
S
S
P
D
P
G
S
A
S
E
Rhesus Macaque
Macaca mulatta
XP_001108628
965
103732
S714
R
E
I
S
R
N
E
S
P
Y
S
M
T
K
P
Dog
Lupus familis
XP_541539
594
63373
Q365
L
D
L
L
D
K
G
Q
V
M
T
G
Y
Y
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZQ0
925
100440
S682
R
E
I
S
R
N
E
S
P
Y
S
M
T
K
P
Rat
Rattus norvegicus
O35800
825
92301
T596
P
P
S
V
S
T
V
T
G
F
Q
Q
T
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512327
625
68790
Q396
N
G
G
Y
I
W
I
Q
S
S
A
T
I
A
I
Chicken
Gallus gallus
Q9YIB9
811
90524
E582
F
D
Q
L
S
P
L
E
S
S
S
S
G
S
Q
Frog
Xenopus laevis
Q9I8A9
805
90946
L576
Q
L
R
T
F
D
Q
L
S
S
L
E
C
D
S
Zebra Danio
Brachydanio rerio
Q98SJ5
745
82716
A516
E
G
V
S
P
H
I
A
S
I
H
S
L
Q
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24119
995
106459
A753
P
P
N
T
D
F
S
A
D
S
L
L
K
Q
Q
Honey Bee
Apis mellifera
XP_391937
963
103825
A727
S
T
I
Q
W
I
G
A
H
H
H
L
G
H
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783845
933
103039
P698
H
N
G
M
I
P
S
P
D
T
N
H
T
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.1
94.7
35.1
N.A.
94
24.2
N.A.
64.1
24.5
20.2
27.4
N.A.
32.4
31
N.A.
33.1
Protein Similarity:
100
40.2
94.9
45.2
N.A.
95.3
41.7
N.A.
64.7
40.2
38.5
41.9
N.A.
46.7
47.4
N.A.
49.3
P-Site Identity:
100
0
100
0
N.A.
100
6.6
N.A.
0
6.6
0
6.6
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
13.3
100
20
N.A.
100
26.6
N.A.
6.6
13.3
26.6
33.3
N.A.
26.6
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
24
0
0
8
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
24
0
0
16
8
0
0
24
0
0
0
0
8
0
% D
% Glu:
16
24
0
0
0
0
24
8
0
0
0
8
0
0
8
% E
% Phe:
8
0
0
0
8
8
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
16
16
0
0
0
16
0
8
0
8
8
16
0
0
% G
% His:
8
0
0
0
0
8
0
0
8
8
16
8
0
8
0
% H
% Ile:
0
0
31
0
16
8
16
0
0
8
0
0
8
0
8
% I
% Lys:
0
0
0
0
0
8
0
0
0
0
0
0
8
24
0
% K
% Leu:
8
8
8
16
0
0
8
8
0
0
16
16
8
0
24
% L
% Met:
0
0
0
8
0
0
0
0
0
8
0
24
0
0
0
% M
% Asn:
8
8
8
0
0
24
0
0
0
0
8
0
0
0
0
% N
% Pro:
16
16
0
0
8
16
0
16
24
8
0
0
0
0
24
% P
% Gln:
8
0
8
8
0
0
8
16
0
0
8
8
0
24
16
% Q
% Arg:
24
0
8
0
24
0
0
0
0
0
0
0
0
8
8
% R
% Ser:
8
0
16
31
16
8
24
24
31
31
31
24
0
16
8
% S
% Thr:
0
8
0
16
0
8
0
8
0
8
8
8
39
0
0
% T
% Val:
0
0
8
16
8
0
8
0
8
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
24
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _