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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPAS3
All Species:
11.82
Human Site:
S748
Identified Species:
21.67
UniProt:
Q8IXF0
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXF0
NP_071406.1
933
100805
S748
P
V
A
S
D
P
L
S
P
P
L
S
A
S
P
Chimpanzee
Pan troglodytes
A2T6X9
766
85495
K601
S
I
N
G
A
G
K
K
H
S
L
C
F
A
N
Rhesus Macaque
Macaca mulatta
XP_001108628
965
103732
S784
P
V
A
S
D
P
L
S
P
P
L
S
A
S
P
Dog
Lupus familis
XP_541539
594
63373
C429
Q
L
P
A
S
V
A
C
E
D
I
S
S
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZQ0
925
100440
S747
P
V
P
S
D
P
L
S
P
P
L
S
A
S
P
Rat
Rattus norvegicus
O35800
825
92301
S660
T
A
K
A
S
A
Y
S
G
T
H
S
R
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512327
625
68790
A460
S
D
S
K
D
N
S
A
A
A
G
P
P
A
P
Chicken
Gallus gallus
Q9YIB9
811
90524
G646
A
P
A
S
P
Y
S
G
N
R
S
R
T
A
S
Frog
Xenopus laevis
Q9I8A9
805
90946
G640
A
P
V
S
P
Y
N
G
N
R
S
R
T
S
S
Zebra Danio
Brachydanio rerio
Q98SJ5
745
82716
S580
Q
M
I
K
E
E
E
S
R
L
Q
L
R
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24119
995
106459
G818
R
Q
T
P
T
G
V
G
P
G
V
F
Y
G
D
Honey Bee
Apis mellifera
XP_391937
963
103825
P793
G
D
T
T
P
S
G
P
L
P
T
P
P
G
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783845
933
103039
S762
A
R
P
T
H
T
D
S
I
T
P
I
F
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.1
94.7
35.1
N.A.
94
24.2
N.A.
64.1
24.5
20.2
27.4
N.A.
32.4
31
N.A.
33.1
Protein Similarity:
100
40.2
94.9
45.2
N.A.
95.3
41.7
N.A.
64.7
40.2
38.5
41.9
N.A.
46.7
47.4
N.A.
49.3
P-Site Identity:
100
6.6
100
6.6
N.A.
93.3
13.3
N.A.
13.3
13.3
13.3
6.6
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
20
100
33.3
N.A.
93.3
26.6
N.A.
33.3
20
13.3
20
N.A.
20
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
8
24
16
8
8
8
8
8
8
0
0
24
24
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% C
% Asp:
0
16
0
0
31
0
8
0
0
8
0
0
0
0
8
% D
% Glu:
0
0
0
0
8
8
8
0
8
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
16
0
0
% F
% Gly:
8
0
0
8
0
16
8
24
8
8
8
0
0
16
0
% G
% His:
0
0
0
0
8
0
0
0
8
0
8
0
0
0
0
% H
% Ile:
0
8
8
0
0
0
0
0
8
0
8
8
0
0
0
% I
% Lys:
0
0
8
16
0
0
8
8
0
0
0
0
0
8
0
% K
% Leu:
0
8
0
0
0
0
24
0
8
8
31
8
0
0
8
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
8
8
0
16
0
0
0
0
0
8
% N
% Pro:
24
16
24
8
24
24
0
8
31
31
8
16
16
8
31
% P
% Gln:
16
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
8
8
0
0
0
0
0
0
8
16
0
16
16
0
0
% R
% Ser:
16
0
8
39
16
8
16
47
0
8
16
39
8
31
24
% S
% Thr:
8
0
16
16
8
8
0
0
0
16
8
0
16
16
8
% T
% Val:
0
24
8
0
0
8
8
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
16
8
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _