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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPAS3
All Species:
11.21
Human Site:
S781
Identified Species:
20.56
UniProt:
Q8IXF0
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXF0
NP_071406.1
933
100805
S781
G
G
G
G
P
S
A
S
N
S
L
L
Y
T
G
Chimpanzee
Pan troglodytes
A2T6X9
766
85495
L624
E
I
C
H
G
S
A
L
A
N
T
S
P
C
D
Rhesus Macaque
Macaca mulatta
XP_001108628
965
103732
S813
G
G
G
G
P
S
A
S
N
S
L
L
Y
T
G
Dog
Lupus familis
XP_541539
594
63373
A452
P
A
E
G
K
Q
A
A
P
L
D
K
D
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZQ0
925
100440
S773
G
G
G
G
P
G
A
S
N
S
L
L
Y
T
G
Rat
Rattus norvegicus
O35800
825
92301
A683
V
I
E
K
T
D
K
A
H
P
R
S
L
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512327
625
68790
C483
R
R
G
P
P
R
A
C
P
G
G
R
P
R
A
Chicken
Gallus gallus
Q9YIB9
811
90524
C669
L
E
Q
T
E
K
S
C
P
G
A
P
S
L
I
Frog
Xenopus laevis
Q9I8A9
805
90946
R663
V
D
K
T
E
K
S
R
P
G
T
P
N
L
P
Zebra Danio
Brachydanio rerio
Q98SJ5
745
82716
F603
T
N
S
L
A
K
S
F
H
S
T
D
F
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24119
995
106459
Y841
P
P
G
S
E
S
S
Y
E
N
Q
Y
L
Q
L
Honey Bee
Apis mellifera
XP_391937
963
103825
H816
H
Q
F
V
L
A
T
H
N
Q
K
S
S
S
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783845
933
103039
T786
T
S
G
S
K
H
E
T
V
Y
P
I
P
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.1
94.7
35.1
N.A.
94
24.2
N.A.
64.1
24.5
20.2
27.4
N.A.
32.4
31
N.A.
33.1
Protein Similarity:
100
40.2
94.9
45.2
N.A.
95.3
41.7
N.A.
64.7
40.2
38.5
41.9
N.A.
46.7
47.4
N.A.
49.3
P-Site Identity:
100
13.3
100
13.3
N.A.
93.3
0
N.A.
20
0
0
6.6
N.A.
13.3
13.3
N.A.
6.6
P-Site Similarity:
100
20
100
20
N.A.
93.3
13.3
N.A.
20
6.6
6.6
26.6
N.A.
26.6
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
8
47
16
8
0
8
0
0
0
16
% A
% Cys:
0
0
8
0
0
0
0
16
0
0
0
0
0
8
0
% C
% Asp:
0
8
0
0
0
8
0
0
0
0
8
8
8
0
8
% D
% Glu:
8
8
16
0
24
0
8
0
8
0
0
0
0
8
0
% E
% Phe:
0
0
8
0
0
0
0
8
0
0
0
0
8
0
0
% F
% Gly:
24
24
47
31
8
8
0
0
0
24
8
0
0
0
31
% G
% His:
8
0
0
8
0
8
0
8
16
0
0
0
0
0
0
% H
% Ile:
0
16
0
0
0
0
0
0
0
0
0
8
0
0
8
% I
% Lys:
0
0
8
8
16
24
8
0
0
0
8
8
0
0
0
% K
% Leu:
8
0
0
8
8
0
0
8
0
8
24
24
16
16
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
31
16
0
0
8
8
0
% N
% Pro:
16
8
0
8
31
0
0
0
31
8
8
16
24
8
16
% P
% Gln:
0
8
8
0
0
8
0
0
0
8
8
0
0
8
8
% Q
% Arg:
8
8
0
0
0
8
0
8
0
0
8
8
0
8
0
% R
% Ser:
0
8
8
16
0
31
31
24
0
31
0
24
16
16
0
% S
% Thr:
16
0
0
16
8
0
8
8
0
0
24
0
0
24
0
% T
% Val:
16
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
8
0
8
24
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _