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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPAS3
All Species:
10.91
Human Site:
T461
Identified Species:
20
UniProt:
Q8IXF0
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXF0
NP_071406.1
933
100805
T461
K
T
S
E
S
S
E
T
S
D
S
E
S
D
S
Chimpanzee
Pan troglodytes
A2T6X9
766
85495
T333
V
S
V
N
Y
V
L
T
D
T
E
Y
K
G
L
Rhesus Macaque
Macaca mulatta
XP_001108628
965
103732
T497
K
T
S
E
S
S
E
T
S
D
S
E
S
D
S
Dog
Lupus familis
XP_541539
594
63373
L161
L
N
Q
E
G
K
F
L
Y
I
S
E
T
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZQ0
925
100440
T466
K
A
S
E
S
S
E
T
S
D
S
E
S
D
S
Rat
Rattus norvegicus
O35800
825
92301
K392
C
L
F
D
K
L
K
K
E
P
D
A
L
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512327
625
68790
E192
V
H
P
G
D
H
V
E
M
A
E
Q
L
G
M
Chicken
Gallus gallus
Q9YIB9
811
90524
D378
M
T
K
I
F
S
K
D
D
W
D
D
T
N
S
Frog
Xenopus laevis
Q9I8A9
805
90946
K371
P
V
E
S
Q
E
I
K
M
P
E
I
F
T
E
Zebra Danio
Brachydanio rerio
Q98SJ5
745
82716
T312
V
W
V
Q
S
Y
A
T
I
V
H
N
S
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24119
995
106459
E546
N
Y
V
I
S
N
R
E
N
E
N
M
I
L
D
Honey Bee
Apis mellifera
XP_391937
963
103825
A522
G
V
K
R
E
D
A
A
G
N
D
P
E
N
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783845
933
103039
G470
D
E
H
I
E
L
L
G
T
S
P
S
R
N
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.1
94.7
35.1
N.A.
94
24.2
N.A.
64.1
24.5
20.2
27.4
N.A.
32.4
31
N.A.
33.1
Protein Similarity:
100
40.2
94.9
45.2
N.A.
95.3
41.7
N.A.
64.7
40.2
38.5
41.9
N.A.
46.7
47.4
N.A.
49.3
P-Site Identity:
100
6.6
100
26.6
N.A.
93.3
0
N.A.
0
20
0
26.6
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
13.3
100
33.3
N.A.
93.3
13.3
N.A.
6.6
46.6
0
33.3
N.A.
33.3
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
16
8
0
8
0
8
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
8
8
0
8
16
24
24
8
0
24
8
% D
% Glu:
0
8
8
31
16
8
24
16
8
8
24
31
8
0
8
% E
% Phe:
0
0
8
0
8
0
8
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
0
8
8
0
0
8
8
0
0
0
0
16
8
% G
% His:
0
8
8
0
0
8
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
24
0
0
8
0
8
8
0
8
8
0
0
% I
% Lys:
24
0
16
0
8
8
16
16
0
0
0
0
8
0
8
% K
% Leu:
8
8
0
0
0
16
16
8
0
0
0
0
16
8
16
% L
% Met:
8
0
0
0
0
0
0
0
16
0
0
8
0
0
8
% M
% Asn:
8
8
0
8
0
8
0
0
8
8
8
8
0
24
0
% N
% Pro:
8
0
8
0
0
0
0
0
0
16
8
8
0
0
0
% P
% Gln:
0
0
8
8
8
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
8
0
0
8
0
0
0
0
0
8
8
0
% R
% Ser:
0
8
24
8
39
31
0
0
24
8
31
8
31
0
47
% S
% Thr:
0
24
0
0
0
0
0
39
8
8
0
0
16
16
0
% T
% Val:
24
16
24
0
0
8
8
0
0
8
0
0
0
8
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
8
0
0
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _