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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPAS3
All Species:
12.12
Human Site:
T650
Identified Species:
22.22
UniProt:
Q8IXF0
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXF0
NP_071406.1
933
100805
T650
A
S
V
L
K
I
K
T
E
I
S
E
P
I
N
Chimpanzee
Pan troglodytes
A2T6X9
766
85495
Y509
S
P
E
S
R
E
A
Y
E
N
S
M
P
H
I
Rhesus Macaque
Macaca mulatta
XP_001108628
965
103732
T686
A
S
V
L
K
I
K
T
E
I
S
E
P
I
N
Dog
Lupus familis
XP_541539
594
63373
V337
D
L
G
P
S
E
L
V
G
R
S
C
Y
Q
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZQ0
925
100440
T654
A
S
V
L
K
I
K
T
E
I
A
E
P
I
N
Rat
Rattus norvegicus
O35800
825
92301
D568
L
A
P
Y
I
P
M
D
D
D
F
Q
L
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512327
625
68790
S368
D
V
E
G
I
R
H
S
H
L
D
L
L
N
K
Chicken
Gallus gallus
Q9YIB9
811
90524
D554
P
F
S
T
Q
E
T
D
L
D
L
E
M
L
A
Frog
Xenopus laevis
Q9I8A9
805
90946
Y548
E
A
K
A
P
F
Y
Y
P
G
N
D
L
D
L
Zebra Danio
Brachydanio rerio
Q98SJ5
745
82716
W488
Q
P
G
R
E
A
W
W
G
A
A
R
S
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24119
995
106459
K725
S
A
A
D
S
A
V
K
D
L
E
Q
A
M
S
Honey Bee
Apis mellifera
XP_391937
963
103825
P699
N
L
N
K
S
H
S
P
T
L
H
Q
P
T
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783845
933
103039
D670
A
S
R
H
E
E
E
D
I
V
R
V
P
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.1
94.7
35.1
N.A.
94
24.2
N.A.
64.1
24.5
20.2
27.4
N.A.
32.4
31
N.A.
33.1
Protein Similarity:
100
40.2
94.9
45.2
N.A.
95.3
41.7
N.A.
64.7
40.2
38.5
41.9
N.A.
46.7
47.4
N.A.
49.3
P-Site Identity:
100
20
100
6.6
N.A.
93.3
0
N.A.
0
6.6
0
0
N.A.
0
6.6
N.A.
20
P-Site Similarity:
100
33.3
100
6.6
N.A.
100
26.6
N.A.
13.3
20
20
20
N.A.
46.6
26.6
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
24
8
8
0
16
8
0
0
8
16
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
16
0
0
8
0
0
0
24
16
16
8
8
0
8
8
% D
% Glu:
8
0
16
0
16
31
8
0
31
0
8
31
0
0
0
% E
% Phe:
0
8
0
0
0
8
0
0
0
0
8
0
0
0
8
% F
% Gly:
0
0
16
8
0
0
0
0
16
8
0
0
0
0
8
% G
% His:
0
0
0
8
0
8
8
0
8
0
8
0
0
8
0
% H
% Ile:
0
0
0
0
16
24
0
0
8
24
0
0
0
24
8
% I
% Lys:
0
0
8
8
24
0
24
8
0
0
0
0
0
0
8
% K
% Leu:
8
16
0
24
0
0
8
0
8
24
8
8
24
16
16
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
8
8
8
0
% M
% Asn:
8
0
8
0
0
0
0
0
0
8
8
0
0
8
24
% N
% Pro:
8
16
8
8
8
8
0
8
8
0
0
0
47
0
0
% P
% Gln:
8
0
0
0
8
0
0
0
0
0
0
24
0
8
0
% Q
% Arg:
0
0
8
8
8
8
0
0
0
8
8
8
0
8
0
% R
% Ser:
16
31
8
8
24
0
8
8
0
0
31
0
8
0
16
% S
% Thr:
0
0
0
8
0
0
8
24
8
0
0
0
0
8
0
% T
% Val:
0
8
24
0
0
0
8
8
0
8
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
8
16
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _