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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPAS3
All Species:
16.36
Human Site:
T825
Identified Species:
30
UniProt:
Q8IXF0
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXF0
NP_071406.1
933
100805
T825
T
A
A
Q
R
V
Y
T
T
G
T
I
R
Y
A
Chimpanzee
Pan troglodytes
A2T6X9
766
85495
S660
T
A
L
S
R
I
S
S
P
N
S
D
R
I
S
Rhesus Macaque
Macaca mulatta
XP_001108628
965
103732
T857
T
A
A
Q
R
V
Y
T
T
G
T
I
R
Y
A
Dog
Lupus familis
XP_541539
594
63373
S488
D
S
G
D
E
E
P
S
S
H
P
A
L
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZQ0
925
100440
T817
T
A
A
Q
R
V
Y
T
T
G
T
I
R
Y
A
Rat
Rattus norvegicus
O35800
825
92301
R719
L
Q
N
A
Q
R
K
R
K
M
E
H
D
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512327
625
68790
T519
Q
R
V
Y
T
T
G
T
I
R
Y
A
P
A
E
Chicken
Gallus gallus
Q9YIB9
811
90524
R705
L
H
N
A
Q
R
K
R
K
M
E
H
D
G
S
Frog
Xenopus laevis
Q9I8A9
805
90946
R699
T
Q
C
T
A
E
K
R
K
M
E
S
D
G
P
Zebra Danio
Brachydanio rerio
Q98SJ5
745
82716
S639
V
P
L
S
R
L
S
S
P
L
P
D
R
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24119
995
106459
Y877
L
V
S
T
Y
G
G
Y
H
S
S
I
D
Y
H
Honey Bee
Apis mellifera
XP_391937
963
103825
S856
S
A
M
T
P
P
S
S
V
S
P
R
D
K
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783845
933
103039
G823
F
Y
N
A
R
M
L
G
V
P
S
S
Y
T
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.1
94.7
35.1
N.A.
94
24.2
N.A.
64.1
24.5
20.2
27.4
N.A.
32.4
31
N.A.
33.1
Protein Similarity:
100
40.2
94.9
45.2
N.A.
95.3
41.7
N.A.
64.7
40.2
38.5
41.9
N.A.
46.7
47.4
N.A.
49.3
P-Site Identity:
100
26.6
100
0
N.A.
100
0
N.A.
6.6
0
6.6
13.3
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
53.3
100
20
N.A.
100
13.3
N.A.
6.6
13.3
6.6
33.3
N.A.
26.6
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
39
24
24
8
0
0
0
0
0
0
16
0
8
24
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
0
0
0
0
0
16
39
0
0
% D
% Glu:
0
0
0
0
8
16
0
0
0
0
24
0
0
0
8
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
8
16
8
0
24
0
0
0
24
0
% G
% His:
0
8
0
0
0
0
0
0
8
8
0
16
0
0
8
% H
% Ile:
0
0
0
0
0
8
0
0
8
0
0
31
0
8
0
% I
% Lys:
0
0
0
0
0
0
24
0
24
0
0
0
0
8
0
% K
% Leu:
24
0
16
0
0
8
8
0
0
8
0
0
8
8
0
% L
% Met:
0
0
8
0
0
8
0
0
0
24
0
0
0
0
0
% M
% Asn:
0
0
24
0
0
0
0
0
0
8
0
0
0
0
8
% N
% Pro:
0
8
0
0
8
8
8
0
16
8
24
0
8
8
8
% P
% Gln:
8
16
0
24
16
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
8
0
0
47
16
0
24
0
8
0
8
39
0
8
% R
% Ser:
8
8
8
16
0
0
24
31
8
16
24
16
0
0
31
% S
% Thr:
39
0
0
24
8
8
0
31
24
0
24
0
0
8
0
% T
% Val:
8
8
8
0
0
24
0
0
16
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
8
8
0
24
8
0
0
8
0
8
31
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _