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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPAS3
All Species:
10
Human Site:
Y353
Identified Species:
18.33
UniProt:
Q8IXF0
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXF0
NP_071406.1
933
100805
Y353
C
E
N
R
I
S
D
Y
M
D
L
T
P
V
D
Chimpanzee
Pan troglodytes
A2T6X9
766
85495
H228
A
V
T
E
I
K
L
H
S
N
M
F
M
F
R
Rhesus Macaque
Macaca mulatta
XP_001108628
965
103732
Y389
C
E
N
R
I
S
D
Y
M
D
L
T
P
V
D
Dog
Lupus familis
XP_541539
594
63373
R56
E
K
S
R
N
A
A
R
S
R
R
G
K
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZQ0
925
100440
Y358
C
E
N
R
I
S
D
Y
M
D
L
T
P
V
D
Rat
Rattus norvegicus
O35800
825
92301
L287
H
A
L
D
S
D
H
L
T
K
T
H
H
D
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512327
625
68790
I87
A
S
I
I
R
L
T
I
S
Y
L
K
M
R
D
Chicken
Gallus gallus
Q9YIB9
811
90524
R273
E
P
E
E
L
L
G
R
S
I
Y
E
Y
Y
H
Frog
Xenopus laevis
Q9I8A9
805
90946
Y266
R
V
T
E
L
V
G
Y
E
P
D
E
L
L
G
Zebra Danio
Brachydanio rerio
Q98SJ5
745
82716
N207
P
F
D
G
C
Y
Q
N
V
G
L
V
A
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24119
995
106459
D440
H
E
I
R
L
E
C
D
M
F
V
T
R
V
N
Honey Bee
Apis mellifera
XP_391937
963
103825
L414
C
E
P
R
V
S
E
L
L
D
Y
T
A
D
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783845
933
103039
F363
C
E
A
K
I
G
D
F
L
D
H
S
A
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.1
94.7
35.1
N.A.
94
24.2
N.A.
64.1
24.5
20.2
27.4
N.A.
32.4
31
N.A.
33.1
Protein Similarity:
100
40.2
94.9
45.2
N.A.
95.3
41.7
N.A.
64.7
40.2
38.5
41.9
N.A.
46.7
47.4
N.A.
49.3
P-Site Identity:
100
6.6
100
6.6
N.A.
100
0
N.A.
13.3
0
6.6
13.3
N.A.
33.3
40
N.A.
33.3
P-Site Similarity:
100
26.6
100
33.3
N.A.
100
0
N.A.
13.3
6.6
20
26.6
N.A.
53.3
66.6
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
8
0
0
8
8
0
0
0
0
0
24
0
0
% A
% Cys:
39
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
8
31
8
0
39
8
0
0
24
31
% D
% Glu:
16
47
8
24
0
8
8
0
8
0
0
16
0
0
8
% E
% Phe:
0
8
0
0
0
0
0
8
0
8
0
8
0
8
0
% F
% Gly:
0
0
0
8
0
8
16
0
0
8
0
8
0
0
16
% G
% His:
16
0
0
0
0
0
8
8
0
0
8
8
8
0
8
% H
% Ile:
0
0
16
8
39
0
0
8
0
8
0
0
0
0
0
% I
% Lys:
0
8
0
8
0
8
0
0
0
8
0
8
8
8
0
% K
% Leu:
0
0
8
0
24
16
8
16
16
0
39
0
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
31
0
8
0
16
0
8
% M
% Asn:
0
0
24
0
8
0
0
8
0
8
0
0
0
0
16
% N
% Pro:
8
8
8
0
0
0
0
0
0
8
0
0
24
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
47
8
0
0
16
0
8
8
0
8
8
8
% R
% Ser:
0
8
8
0
8
31
0
0
31
0
0
8
0
0
8
% S
% Thr:
0
0
16
0
0
0
8
0
8
0
8
39
0
0
0
% T
% Val:
0
16
0
0
8
8
0
0
8
0
8
8
0
39
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
31
0
8
16
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _