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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TH1L
All Species:
21.52
Human Site:
Y56
Identified Species:
78.89
UniProt:
Q8IXH7
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXH7
NP_945327.1
590
66247
Y56
H
K
F
S
T
R
D
Y
I
M
E
P
S
I
F
Chimpanzee
Pan troglodytes
XP_001139660
599
67317
Y65
H
K
F
S
T
R
D
Y
I
M
E
P
S
I
F
Rhesus Macaque
Macaca mulatta
XP_001084700
567
63384
Y65
H
K
F
S
T
R
D
Y
I
M
E
P
S
I
F
Dog
Lupus familis
XP_534468
585
65921
Y51
H
K
F
S
T
R
D
Y
I
M
E
P
S
I
F
Cat
Felis silvestris
Mouse
Mus musculus
Q922L6
591
66257
Y57
H
K
F
S
T
R
D
Y
I
M
E
P
S
I
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24134
578
65762
Y44
E
K
F
L
T
P
D
Y
I
M
E
P
G
I
F
Honey Bee
Apis mellifera
XP_394889
445
50388
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
94
95.4
N.A.
97.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
53.2
43.5
N.A.
N.A.
Protein Similarity:
100
98.5
94.2
96.4
N.A.
98.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
74.7
61.5
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
73.3
0
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
73.3
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
86
0
0
0
0
0
0
0
0
% D
% Glu:
15
0
0
0
0
0
0
0
0
0
86
0
0
0
0
% E
% Phe:
0
0
86
0
0
0
0
0
0
0
0
0
0
0
86
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% G
% His:
72
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
86
0
0
0
0
86
0
% I
% Lys:
0
86
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
86
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
15
0
0
0
0
0
86
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
72
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
72
0
0
0
0
0
0
0
0
72
0
0
% S
% Thr:
0
0
0
0
86
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
86
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _