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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RHOT2
All Species:
38.48
Human Site:
S196
Identified Species:
60.48
UniProt:
Q8IXI1
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXI1
NP_620124.1
618
68118
S196
L
T
R
I
F
R
L
S
D
Q
D
L
D
Q
A
Chimpanzee
Pan troglodytes
XP_510715
616
67803
S196
L
T
R
I
F
R
L
S
D
Q
D
L
D
Q
A
Rhesus Macaque
Macaca mulatta
XP_001118510
455
50332
Y47
L
H
P
T
A
P
L
Y
D
P
E
A
K
Q
L
Dog
Lupus familis
XP_537019
616
67891
S192
L
T
R
I
F
R
L
S
D
R
D
L
D
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZN7
620
69053
S196
L
T
R
I
F
R
L
S
D
Q
D
R
D
H
G
Rat
Rattus norvegicus
Q7TSA0
622
69135
S196
L
T
R
I
F
R
L
S
D
Q
D
L
D
H
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511136
687
78991
S198
L
T
R
I
F
R
I
S
D
Q
D
N
D
G
T
Chicken
Gallus gallus
Q5ZM83
618
69052
S196
L
T
R
I
F
N
L
S
D
Q
D
N
N
Q
I
Frog
Xenopus laevis
NP_001121318
618
70967
S196
L
T
R
I
F
K
I
S
D
M
D
N
D
R
I
Zebra Danio
Brachydanio rerio
Q32LU1
617
69721
S196
L
S
R
I
F
S
I
S
D
Q
D
N
D
H
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IMX7
652
73757
C222
L
V
R
I
F
K
I
C
D
I
D
G
D
N
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94263
625
70204
C200
L
I
R
V
F
K
I
C
D
R
D
N
D
G
Y
Sea Urchin
Strong. purpuratus
XP_791124
583
66070
P175
A
V
L
H
P
T
G
P
L
Y
S
A
E
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39722
662
75132
S213
L
K
R
I
F
L
L
S
D
L
N
Q
D
S
Y
Red Bread Mold
Neurospora crassa
Q7RZA2
629
70228
S198
L
R
R
I
F
F
L
S
D
K
D
Q
D
G
Y
Conservation
Percent
Protein Identity:
100
97.4
69.5
83.9
N.A.
85
84.2
N.A.
53.8
73.4
60.8
65.5
N.A.
47
N.A.
44.6
52.4
Protein Similarity:
100
97.9
70.3
87.8
N.A.
90.6
89.8
N.A.
67.6
83.5
75.2
77.8
N.A.
64.4
N.A.
62.5
65.8
P-Site Identity:
100
100
26.6
93.3
N.A.
80
93.3
N.A.
73.3
73.3
60
60
N.A.
46.6
N.A.
40
0
P-Site Similarity:
100
100
33.3
100
N.A.
80
93.3
N.A.
80
80
80
73.3
N.A.
60
N.A.
66.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.9
35.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.5
54.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
60
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
0
0
0
0
0
0
14
0
0
27
% A
% Cys:
0
0
0
0
0
0
0
14
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
94
0
80
0
80
7
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% E
% Phe:
0
0
0
0
87
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
7
0
0
0
0
7
0
20
7
% G
% His:
0
7
0
7
0
0
0
0
0
0
0
0
0
20
0
% H
% Ile:
0
7
0
80
0
0
34
0
0
7
0
0
0
0
20
% I
% Lys:
0
7
0
0
0
20
0
0
0
7
0
0
7
0
7
% K
% Leu:
94
0
7
0
0
7
60
0
7
7
0
27
0
0
14
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
0
0
7
34
7
7
0
% N
% Pro:
0
0
7
0
7
7
0
7
0
7
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
47
0
14
0
34
0
% Q
% Arg:
0
7
87
0
0
40
0
0
0
14
0
7
0
7
0
% R
% Ser:
0
7
0
0
0
7
0
74
0
0
7
0
0
7
0
% S
% Thr:
0
54
0
7
0
7
0
0
0
0
0
0
0
0
7
% T
% Val:
0
14
0
7
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _