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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RHOT2 All Species: 46.06
Human Site: S59 Identified Species: 72.38
UniProt: Q8IXI1 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IXI1 NP_620124.1 618 68118 S59 P T H I V D Y S E A E Q T D E
Chimpanzee Pan troglodytes XP_510715 616 67803 S59 P T H I V D Y S E A E Q T D E
Rhesus Macaque Macaca mulatta XP_001118510 455 50332
Dog Lupus familis XP_537019 616 67891 S55 P T H I V D Y S E A E Q T A E
Cat Felis silvestris
Mouse Mus musculus Q8JZN7 620 69053 S59 P T H I V D Y S E A E Q T E E
Rat Rattus norvegicus Q7TSA0 622 69135 S59 P T H I V D Y S E A E Q T E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511136 687 78991 S61 P T H I V D Y S E A E Q S D E
Chicken Gallus gallus Q5ZM83 618 69052 S59 P T H I V D Y S E S E Q T E D
Frog Xenopus laevis NP_001121318 618 70967 S59 P T H I V D Y S E A E Q T D D
Zebra Danio Brachydanio rerio Q32LU1 617 69721 S59 P T H I V D Y S E N E Q T D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IMX7 652 73757 S66 P T S I V D F S A V E Q S E D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q94263 625 70204 S64 T T S I V D L S I K E E D E N
Sea Urchin Strong. purpuratus XP_791124 583 66070 E42 E V P A R A E E I T I P P D V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39722 662 75132 S64 N T V L I D T S D S D L I A L
Red Bread Mold Neurospora crassa Q7RZA2 629 70228 S61 T T T I V D T S A R P Q D R T
Conservation
Percent
Protein Identity: 100 97.4 69.5 83.9 N.A. 85 84.2 N.A. 53.8 73.4 60.8 65.5 N.A. 47 N.A. 44.6 52.4
Protein Similarity: 100 97.9 70.3 87.8 N.A. 90.6 89.8 N.A. 67.6 83.5 75.2 77.8 N.A. 64.4 N.A. 62.5 65.8
P-Site Identity: 100 100 0 93.3 N.A. 93.3 93.3 N.A. 93.3 80 93.3 93.3 N.A. 53.3 N.A. 40 6.6
P-Site Similarity: 100 100 0 93.3 N.A. 100 100 N.A. 100 100 100 93.3 N.A. 80 N.A. 53.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 29.9 35.4
Protein Similarity: N.A. N.A. N.A. N.A. 47.5 54.8
P-Site Identity: N.A. N.A. N.A. N.A. 20 40
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 7 0 0 14 47 0 0 0 14 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 87 0 0 7 0 7 0 14 40 20 % D
% Glu: 7 0 0 0 0 0 7 7 60 0 74 7 0 34 47 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 60 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 80 7 0 0 0 14 0 7 0 7 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % K
% Leu: 0 0 0 7 0 0 7 0 0 0 0 7 0 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 0 0 0 0 0 7 0 0 0 0 7 % N
% Pro: 67 0 7 0 0 0 0 0 0 0 7 7 7 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 74 0 0 0 % Q
% Arg: 0 0 0 0 7 0 0 0 0 7 0 0 0 7 0 % R
% Ser: 0 0 14 0 0 0 0 87 0 14 0 0 14 0 0 % S
% Thr: 14 87 7 0 0 0 14 0 0 7 0 0 54 0 7 % T
% Val: 0 7 7 0 80 0 0 0 0 7 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 60 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _