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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RHOT2
All Species:
41.21
Human Site:
Y174
Identified Species:
64.76
UniProt:
Q8IXI1
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXI1
NP_620124.1
618
68118
Y174
L
H
P
T
A
P
L
Y
D
P
E
A
K
Q
L
Chimpanzee
Pan troglodytes
XP_510715
616
67803
Y174
L
H
P
T
A
P
L
Y
D
P
E
A
K
Q
L
Rhesus Macaque
Macaca mulatta
XP_001118510
455
50332
R26
E
C
S
A
R
N
L
R
N
I
S
E
L
F
Y
Dog
Lupus familis
XP_537019
616
67891
Y170
L
H
P
T
A
P
L
Y
D
P
E
A
K
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZN7
620
69053
Y174
L
H
P
T
A
P
L
Y
D
P
E
A
K
Q
L
Rat
Rattus norvegicus
Q7TSA0
622
69135
Y174
L
H
P
T
A
P
L
Y
D
P
E
A
K
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511136
687
78991
Y176
L
H
P
T
G
P
L
Y
C
P
E
E
K
E
M
Chicken
Gallus gallus
Q5ZM83
618
69052
Y174
L
H
P
T
A
P
L
Y
D
P
E
E
K
Q
L
Frog
Xenopus laevis
NP_001121318
618
70967
Y174
L
H
P
T
G
P
L
Y
C
P
E
E
K
E
L
Zebra Danio
Brachydanio rerio
Q32LU1
617
69721
Y174
L
H
P
T
A
P
L
Y
D
P
E
D
K
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IMX7
652
73757
Y200
L
H
P
T
S
P
L
Y
M
M
E
E
Q
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94263
625
70204
Y178
I
Y
P
T
R
P
L
Y
D
A
D
T
K
Q
L
Sea Urchin
Strong. purpuratus
XP_791124
583
66070
N154
C
V
E
C
S
A
K
N
L
K
N
I
S
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39722
662
75132
F191
T
H
P
I
S
P
L
F
D
A
M
V
G
E
L
Red Bread Mold
Neurospora crassa
Q7RZA2
629
70228
F176
T
H
P
I
A
P
L
F
D
Y
K
E
G
Q
L
Conservation
Percent
Protein Identity:
100
97.4
69.5
83.9
N.A.
85
84.2
N.A.
53.8
73.4
60.8
65.5
N.A.
47
N.A.
44.6
52.4
Protein Similarity:
100
97.9
70.3
87.8
N.A.
90.6
89.8
N.A.
67.6
83.5
75.2
77.8
N.A.
64.4
N.A.
62.5
65.8
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
66.6
93.3
73.3
93.3
N.A.
60
N.A.
60
0
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
80
93.3
80
93.3
N.A.
80
N.A.
80
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.9
35.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.5
54.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
54
7
0
0
0
14
0
34
0
0
0
% A
% Cys:
7
7
0
7
0
0
0
0
14
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
67
0
7
7
0
0
0
% D
% Glu:
7
0
7
0
0
0
0
0
0
0
67
40
0
34
0
% E
% Phe:
0
0
0
0
0
0
0
14
0
0
0
0
0
7
0
% F
% Gly:
0
0
0
0
14
0
0
0
0
0
0
0
14
0
0
% G
% His:
0
80
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
14
0
0
0
0
0
7
0
7
0
0
0
% I
% Lys:
0
0
0
0
0
0
7
0
0
7
7
0
67
0
0
% K
% Leu:
67
0
0
0
0
0
94
0
7
0
0
0
7
0
80
% L
% Met:
0
0
0
0
0
0
0
0
7
7
7
0
0
0
7
% M
% Asn:
0
0
0
0
0
7
0
7
7
0
7
0
0
0
0
% N
% Pro:
0
0
87
0
0
87
0
0
0
60
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
7
60
0
% Q
% Arg:
0
0
0
0
14
0
0
7
0
0
0
0
0
0
0
% R
% Ser:
0
0
7
0
20
0
0
0
0
0
7
0
7
0
0
% S
% Thr:
14
0
0
74
0
0
0
0
0
0
0
7
0
0
0
% T
% Val:
0
7
0
0
0
0
0
0
0
0
0
7
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
74
0
7
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _