KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RHOT2
All Species:
40.3
Human Site:
Y58
Identified Species:
63.33
UniProt:
Q8IXI1
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXI1
NP_620124.1
618
68118
Y58
V
P
T
H
I
V
D
Y
S
E
A
E
Q
T
D
Chimpanzee
Pan troglodytes
XP_510715
616
67803
Y58
V
P
T
H
I
V
D
Y
S
E
A
E
Q
T
D
Rhesus Macaque
Macaca mulatta
XP_001118510
455
50332
Dog
Lupus familis
XP_537019
616
67891
Y54
V
P
T
H
I
V
D
Y
S
E
A
E
Q
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZN7
620
69053
Y58
V
P
T
H
I
V
D
Y
S
E
A
E
Q
T
E
Rat
Rattus norvegicus
Q7TSA0
622
69135
Y58
V
P
T
H
I
V
D
Y
S
E
A
E
Q
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511136
687
78991
Y60
V
P
T
H
I
V
D
Y
S
E
A
E
Q
S
D
Chicken
Gallus gallus
Q5ZM83
618
69052
Y58
V
P
T
H
I
V
D
Y
S
E
S
E
Q
T
E
Frog
Xenopus laevis
NP_001121318
618
70967
Y58
V
P
T
H
I
V
D
Y
S
E
A
E
Q
T
D
Zebra Danio
Brachydanio rerio
Q32LU1
617
69721
Y58
V
P
T
H
I
V
D
Y
S
E
N
E
Q
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IMX7
652
73757
F65
V
P
T
S
I
V
D
F
S
A
V
E
Q
S
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94263
625
70204
L63
V
T
T
S
I
V
D
L
S
I
K
E
E
D
E
Sea Urchin
Strong. purpuratus
XP_791124
583
66070
E41
E
E
V
P
A
R
A
E
E
I
T
I
P
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39722
662
75132
T63
K
N
T
V
L
I
D
T
S
D
S
D
L
I
A
Red Bread Mold
Neurospora crassa
Q7RZA2
629
70228
T60
V
T
T
T
I
V
D
T
S
A
R
P
Q
D
R
Conservation
Percent
Protein Identity:
100
97.4
69.5
83.9
N.A.
85
84.2
N.A.
53.8
73.4
60.8
65.5
N.A.
47
N.A.
44.6
52.4
Protein Similarity:
100
97.9
70.3
87.8
N.A.
90.6
89.8
N.A.
67.6
83.5
75.2
77.8
N.A.
64.4
N.A.
62.5
65.8
P-Site Identity:
100
100
0
93.3
N.A.
93.3
93.3
N.A.
93.3
86.6
100
93.3
N.A.
60
N.A.
46.6
6.6
P-Site Similarity:
100
100
0
93.3
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
80
N.A.
60
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.9
35.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.5
54.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
7
0
0
14
47
0
0
0
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
87
0
0
7
0
7
0
14
40
% D
% Glu:
7
7
0
0
0
0
0
7
7
60
0
74
7
0
34
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
60
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
80
7
0
0
0
14
0
7
0
7
0
% I
% Lys:
7
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% K
% Leu:
0
0
0
0
7
0
0
7
0
0
0
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
0
0
0
0
7
0
0
0
0
% N
% Pro:
0
67
0
7
0
0
0
0
0
0
0
7
7
7
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
74
0
0
% Q
% Arg:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
7
% R
% Ser:
0
0
0
14
0
0
0
0
87
0
14
0
0
14
0
% S
% Thr:
0
14
87
7
0
0
0
14
0
0
7
0
0
54
0
% T
% Val:
80
0
7
7
0
80
0
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _