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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RHOT1
All Species:
31.52
Human Site:
S238
Identified Species:
49.52
UniProt:
Q8IXI2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXI2
NP_001028738.1
618
70784
S238
N
V
V
R
K
H
I
S
D
G
V
A
D
S
G
Chimpanzee
Pan troglodytes
XP_511399
695
80129
S242
N
V
V
R
K
H
I
S
D
G
V
A
D
S
G
Rhesus Macaque
Macaca mulatta
XP_001109912
830
94570
S377
N
V
V
R
K
H
I
S
D
G
V
A
D
S
G
Dog
Lupus familis
XP_867966
631
72105
S251
N
V
V
R
K
H
I
S
D
G
V
A
D
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG51
631
72223
S251
N
V
V
R
K
H
L
S
D
G
V
A
D
S
G
Rat
Rattus norvegicus
Q7TSA0
622
69135
A238
R
V
V
C
K
N
V
A
G
G
V
Q
D
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511136
687
78991
S240
N
V
V
R
K
N
L
S
D
G
V
A
D
S
G
Chicken
Gallus gallus
Q5ZM73
619
70876
S238
N
V
V
R
K
N
V
S
D
G
V
A
D
N
G
Frog
Xenopus laevis
NP_001121318
618
70967
H238
N
V
V
R
K
N
V
H
D
G
V
S
G
N
G
Zebra Danio
Brachydanio rerio
Q6NVC5
619
71179
T238
N
V
V
R
K
N
M
T
D
G
V
K
D
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IMX7
652
73757
P264
A
V
I
Q
K
N
V
P
D
G
I
Y
N
D
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94263
625
70204
P242
R
A
V
S
D
G
C
P
D
G
V
A
N
D
S
Sea Urchin
Strong. purpuratus
XP_791124
583
66070
F215
N
D
Y
E
L
N
L
F
Q
R
R
C
F
N
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39722
662
75132
K264
D
Q
E
Y
I
N
R
K
L
Y
V
P
G
K
G
Red Bread Mold
Neurospora crassa
Q7RZA2
629
70228
P240
L
T
V
S
K
S
V
P
S
S
S
T
D
K
G
Conservation
Percent
Protein Identity:
100
87
74.3
96.6
N.A.
95.8
58
N.A.
85.5
93.8
85.5
85.9
N.A.
50.6
N.A.
44
59.5
Protein Similarity:
100
88.1
74.4
97.4
N.A.
97.6
75
N.A.
87.9
97.7
94.1
94.8
N.A.
68.8
N.A.
64.1
72.9
P-Site Identity:
100
100
100
100
N.A.
93.3
40
N.A.
86.6
80
60
66.6
N.A.
26.6
N.A.
33.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
60
N.A.
100
100
86.6
93.3
N.A.
66.6
N.A.
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.1
34.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.8
53.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
0
0
7
0
0
0
54
0
0
14
% A
% Cys:
0
0
0
7
0
0
7
0
0
0
0
7
0
0
0
% C
% Asp:
7
7
0
0
7
0
0
0
74
0
0
0
67
20
0
% D
% Glu:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
7
0
0
% F
% Gly:
0
0
0
0
0
7
0
0
7
80
0
0
14
0
74
% G
% His:
0
0
0
0
0
34
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
7
0
27
0
0
0
7
0
0
0
0
% I
% Lys:
0
0
0
0
80
0
0
7
0
0
0
7
0
14
0
% K
% Leu:
7
0
0
0
7
0
20
0
7
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
67
0
0
0
0
54
0
0
0
0
0
0
14
27
0
% N
% Pro:
0
0
0
0
0
0
0
20
0
0
0
7
0
0
0
% P
% Gln:
0
7
0
7
0
0
0
0
7
0
0
7
0
0
0
% Q
% Arg:
14
0
0
60
0
0
7
0
0
7
7
0
0
0
7
% R
% Ser:
0
0
0
14
0
7
0
47
7
7
7
7
0
40
7
% S
% Thr:
0
7
0
0
0
0
0
7
0
0
0
7
0
0
0
% T
% Val:
0
74
80
0
0
0
34
0
0
0
80
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
7
0
0
0
0
0
7
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _