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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RHOT1
All Species:
21.82
Human Site:
T543
Identified Species:
34.29
UniProt:
Q8IXI2
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXI2
NP_001028738.1
618
70784
T543
Q
E
Y
S
I
S
P
T
D
F
C
R
K
H
K
Chimpanzee
Pan troglodytes
XP_511399
695
80129
T547
Q
E
Y
S
I
S
P
T
D
F
C
R
K
H
K
Rhesus Macaque
Macaca mulatta
XP_001109912
830
94570
T682
Q
E
Y
S
I
S
P
T
D
F
C
R
K
H
K
Dog
Lupus familis
XP_867966
631
72105
A556
Q
D
Y
S
I
S
P
A
D
F
C
R
K
H
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG51
631
72223
T556
Q
E
H
S
I
S
P
T
D
F
C
R
K
H
K
Rat
Rattus norvegicus
Q7TSA0
622
69135
A544
A
P
P
G
L
S
P
A
E
F
C
R
R
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511136
687
78991
S545
Q
E
Y
S
I
S
P
S
D
F
C
R
K
H
K
Chicken
Gallus gallus
Q5ZM73
619
70876
A544
Q
E
Y
S
I
S
P
A
E
F
C
K
K
H
K
Frog
Xenopus laevis
NP_001121318
618
70967
A543
Q
E
S
S
I
S
P
A
E
F
C
K
K
H
K
Zebra Danio
Brachydanio rerio
Q6NVC5
619
71179
L544
Q
Y
Y
S
L
S
P
L
D
F
C
R
K
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IMX7
652
73757
S574
Q
D
Y
L
M
Q
P
S
E
F
C
D
K
Y
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94263
625
70204
V550
E
V
D
Q
R
W
E
V
P
P
E
E
F
C
R
Sea Urchin
Strong. purpuratus
XP_791124
583
66070
F509
D
I
S
D
P
R
T
F
E
Y
C
A
K
I
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39722
662
75132
D576
Q
R
C
Q
I
Q
P
D
E
L
A
D
E
L
F
Red Bread Mold
Neurospora crassa
Q7RZA2
629
70228
D551
Q
R
S
E
L
Q
P
D
A
Y
T
A
A
L
N
Conservation
Percent
Protein Identity:
100
87
74.3
96.6
N.A.
95.8
58
N.A.
85.5
93.8
85.5
85.9
N.A.
50.6
N.A.
44
59.5
Protein Similarity:
100
88.1
74.4
97.4
N.A.
97.6
75
N.A.
87.9
97.7
94.1
94.8
N.A.
68.8
N.A.
64.1
72.9
P-Site Identity:
100
100
100
86.6
N.A.
93.3
40
N.A.
93.3
80
73.3
80
N.A.
46.6
N.A.
0
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
100
66.6
N.A.
100
93.3
86.6
86.6
N.A.
80
N.A.
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.1
34.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.8
53.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
27
7
0
7
14
7
0
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
80
0
0
7
0
% C
% Asp:
7
14
7
7
0
0
0
14
47
0
0
14
0
0
0
% D
% Glu:
7
47
0
7
0
0
7
0
40
0
7
7
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
74
0
0
7
0
7
% F
% Gly:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
0
67
0
% H
% Ile:
0
7
0
0
60
0
0
0
0
0
0
0
0
7
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
14
74
0
67
% K
% Leu:
0
0
0
7
20
0
0
7
0
7
0
0
0
14
0
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% N
% Pro:
0
7
7
0
7
0
87
0
7
7
0
0
0
0
0
% P
% Gln:
80
0
0
14
0
20
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
14
0
0
7
7
0
0
0
0
0
54
7
0
14
% R
% Ser:
0
0
20
60
0
67
0
14
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
7
27
0
0
7
0
0
0
0
% T
% Val:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
54
0
0
0
0
0
0
14
0
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _