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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RHOT1 All Species: 36.06
Human Site: Y380 Identified Species: 56.67
UniProt: Q8IXI2 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IXI2 NP_001028738.1 618 70784 Y380 D V Q R C L E Y L G Y L G Y S
Chimpanzee Pan troglodytes XP_511399 695 80129 Y384 D V Q R C L E Y L G Y L G Y S
Rhesus Macaque Macaca mulatta XP_001109912 830 94570 Y519 D V Q R C L E Y L G Y L G Y S
Dog Lupus familis XP_867966 631 72105 Y393 D V Q R C L E Y L G Y L G Y S
Cat Felis silvestris
Mouse Mus musculus Q8BG51 631 72223 Y393 D V Q R C L E Y L G Y L G Y S
Rat Rattus norvegicus Q7TSA0 622 69135 L380 V Q H C L A H L G Y L G Y P T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511136 687 78991 Y382 D V Q R C L E Y L G Y L G Y S
Chicken Gallus gallus Q5ZM73 619 70876 E380 L D V Q R C L E Y L G Y L G Y
Frog Xenopus laevis NP_001121318 618 70967 Y380 D V Q R C L E Y L G Y L G Y S
Zebra Danio Brachydanio rerio Q6NVC5 619 71179 Y380 D V Q R C L E Y L G Y L G Y S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IMX7 652 73757 T406 T L I D V V K T M E Y L A Y L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q94263 625 70204 Q384 N L T Q T F E Q L A Y L G F P
Sea Urchin Strong. purpuratus XP_791124 583 66070 K357 M T V C T N E K G W I T L H G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39722 662 75132 T406 T F L N Y S T T T A Y L V Y F
Red Bread Mold Neurospora crassa Q7RZA2 629 70228 T382 T F L E P K T T L E Y L A Y L
Conservation
Percent
Protein Identity: 100 87 74.3 96.6 N.A. 95.8 58 N.A. 85.5 93.8 85.5 85.9 N.A. 50.6 N.A. 44 59.5
Protein Similarity: 100 88.1 74.4 97.4 N.A. 97.6 75 N.A. 87.9 97.7 94.1 94.8 N.A. 68.8 N.A. 64.1 72.9
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 100 0 100 100 N.A. 20 N.A. 33.3 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 6.6 N.A. 100 6.6 100 100 N.A. 46.6 N.A. 60 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 31.1 34.5
Protein Similarity: N.A. N.A. N.A. N.A. 49.8 53.9
P-Site Identity: N.A. N.A. N.A. N.A. 20 26.6
P-Site Similarity: N.A. N.A. N.A. N.A. 20 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 7 0 0 0 14 0 0 14 0 0 % A
% Cys: 0 0 0 14 54 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 54 7 0 7 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 7 0 0 67 7 0 14 0 0 0 0 0 % E
% Phe: 0 14 0 0 0 7 0 0 0 0 0 0 0 7 7 % F
% Gly: 0 0 0 0 0 0 0 0 14 54 7 7 60 7 7 % G
% His: 0 0 7 0 0 0 7 0 0 0 0 0 0 7 0 % H
% Ile: 0 0 7 0 0 0 0 0 0 0 7 0 0 0 0 % I
% Lys: 0 0 0 0 0 7 7 7 0 0 0 0 0 0 0 % K
% Leu: 7 14 14 0 7 54 7 7 67 7 7 80 14 0 14 % L
% Met: 7 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % M
% Asn: 7 0 0 7 0 7 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 7 0 0 0 0 0 0 0 0 7 7 % P
% Gln: 0 7 54 14 0 0 0 7 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 54 7 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 54 % S
% Thr: 20 7 7 0 14 0 14 20 7 0 0 7 0 0 7 % T
% Val: 7 54 14 0 7 7 0 0 0 0 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 54 7 7 80 7 7 74 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _