KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHC2
All Species:
19.7
Human Site:
T218
Identified Species:
43.33
UniProt:
Q8IXK0
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXK0
NP_004418.2
858
90713
T218
G
S
P
A
R
P
P
T
P
A
Q
V
Q
N
L
Chimpanzee
Pan troglodytes
XP_513294
858
90655
T218
G
S
P
A
R
P
P
T
P
A
Q
V
Q
N
L
Rhesus Macaque
Macaca mulatta
XP_001107739
858
90492
T218
G
S
P
A
R
P
P
T
P
A
Q
V
Q
N
L
Dog
Lupus familis
XP_544423
857
90912
N219
P
T
P
A
Q
V
Q
N
L
T
L
R
T
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9QWH1
850
89781
T221
G
S
P
A
R
P
P
T
P
A
Q
V
Q
N
L
Rat
Rattus norvegicus
NP_001013187
850
90111
T218
G
S
P
A
R
P
P
T
P
A
Q
V
Q
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520216
352
38784
Chicken
Gallus gallus
NP_001006249
991
104697
A300
Q
T
A
S
A
G
V
A
G
S
C
Q
R
K
G
Frog
Xenopus laevis
Q4V7W5
344
37913
Zebra Danio
Brachydanio rerio
Q8QHL5
827
88661
T219
F
T
P
T
A
S
V
T
A
I
Q
P
E
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P39769
1589
167263
P572
Q
I
I
L
R
N
Q
P
D
G
T
Q
G
M
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.3
91.6
N.A.
87
88
N.A.
36.3
32.3
28.7
43.3
N.A.
20.5
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
98.7
94
N.A.
90
90.7
N.A.
37.4
45.3
33.4
55.4
N.A.
31.1
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
100
100
N.A.
0
0
0
20
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
0
26.6
0
33.3
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
55
19
0
0
10
10
46
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
46
0
0
0
0
10
0
0
10
10
0
0
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
0
10
0
0
0
0
10
0
10
0
0
0
46
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
10
0
10
0
0
0
0
0
46
0
% N
% Pro:
10
0
64
0
0
46
46
10
46
0
0
10
0
0
10
% P
% Gln:
19
0
0
0
10
0
19
0
0
0
55
19
46
10
10
% Q
% Arg:
0
0
0
0
55
0
0
0
0
0
0
10
10
0
0
% R
% Ser:
0
46
0
10
0
10
0
0
0
10
0
0
0
0
0
% S
% Thr:
0
28
0
10
0
0
0
55
0
10
10
0
10
0
0
% T
% Val:
0
0
0
0
0
10
19
0
0
0
0
46
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _