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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NRM All Species: 30
Human Site: S185 Identified Species: 66
UniProt: Q8IXM6 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IXM6 NP_009174.1 262 29379 S185 G E P L A L K S P R A L R L F
Chimpanzee Pan troglodytes Q1XHX8 262 29346 S185 G E P L A L K S P R A L R L F
Rhesus Macaque Macaca mulatta Q5TM67 262 29328 S185 G E P L A L K S P R A L R L F
Dog Lupus familis XP_538828 262 29384 S185 G E P L A L K S P R A L R L F
Cat Felis silvestris
Mouse Mus musculus Q8VC65 262 29416 S185 G E P L S L K S P R A L R L F
Rat Rattus norvegicus Q6MG14 262 29363 S185 G E P L S L K S P R A L R L F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510146 160 17796 A84 P R A L R L F A H L R H P V C
Chicken Gallus gallus
Frog Xenopus laevis Q6GNM0 285 32051 S201 G D P L S H K S P R V A R L Y
Zebra Danio Brachydanio rerio Q1L911 275 31162 S190 G D P L L L K S E R A Q R L Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VEG9 253 28551 P176 Y D L K A Y G P P I S Y K S G
Honey Bee Apis mellifera XP_001121274 176 21172 I100 D I S E L A G I K Q V Y Y K F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.7 95.4 N.A. 94.2 93.5 N.A. 43.5 N.A. 48.7 49.8 N.A. 33.5 24.4 N.A. N.A.
Protein Similarity: 100 100 99.2 96.9 N.A. 96.1 95.8 N.A. 47.7 N.A. 63.1 62.5 N.A. 50.7 43.1 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 13.3 N.A. 60 66.6 N.A. 13.3 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 26.6 N.A. 80 80 N.A. 33.3 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 46 10 0 10 0 0 64 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 10 28 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 55 0 10 0 0 0 0 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 64 % F
% Gly: 73 0 0 0 0 0 19 0 0 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 10 0 0 10 0 0 10 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 10 0 10 0 0 0 0 0 % I
% Lys: 0 0 0 10 0 0 73 0 10 0 0 0 10 10 0 % K
% Leu: 0 0 10 82 19 73 0 0 0 10 0 55 0 73 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 73 0 0 0 0 10 73 0 0 0 10 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % Q
% Arg: 0 10 0 0 10 0 0 0 0 73 10 0 73 0 0 % R
% Ser: 0 0 10 0 28 0 0 73 0 0 10 0 0 10 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 19 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 10 0 0 0 0 0 19 10 0 19 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _