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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NRM All Species: 26.97
Human Site: Y227 Identified Species: 59.33
UniProt: Q8IXM6 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IXM6 NP_009174.1 262 29379 Y227 L A F L L T L Y L G L A H G L
Chimpanzee Pan troglodytes Q1XHX8 262 29346 Y227 L A F L L T L Y L G L A H G L
Rhesus Macaque Macaca mulatta Q5TM67 262 29328 Y227 L A L L L T L Y L G L A H G L
Dog Lupus familis XP_538828 262 29384 Y227 L A L L L T L Y L G L A H G L
Cat Felis silvestris
Mouse Mus musculus Q8VC65 262 29416 Y227 L A L L F T L Y L G L A H G L
Rat Rattus norvegicus Q6MG14 262 29363 Y227 L A L L F T L Y L G L A H G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510146 160 17796 D126 L G L A H S L D Q H D L H Y L
Chicken Gallus gallus
Frog Xenopus laevis Q6GNM0 285 32051 Y243 L A I F F T L Y L S L V H R L
Zebra Danio Brachydanio rerio Q1L911 275 31162 Y232 L A V F L T V Y L I L A H S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VEG9 253 28551 A218 S V D R L V M A L L L T T Y M
Honey Bee Apis mellifera XP_001121274 176 21172 I142 G F L I I L W I Y P Y M T L D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.7 95.4 N.A. 94.2 93.5 N.A. 43.5 N.A. 48.7 49.8 N.A. 33.5 24.4 N.A. N.A.
Protein Similarity: 100 100 99.2 96.9 N.A. 96.1 95.8 N.A. 47.7 N.A. 63.1 62.5 N.A. 50.7 43.1 N.A. N.A.
P-Site Identity: 100 100 93.3 93.3 N.A. 86.6 86.6 N.A. 26.6 N.A. 60 66.6 N.A. 20 0 N.A. N.A.
P-Site Similarity: 100 100 93.3 93.3 N.A. 86.6 86.6 N.A. 33.3 N.A. 60 73.3 N.A. 33.3 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 73 0 10 0 0 0 10 0 0 0 64 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 10 0 0 10 0 0 0 10 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 10 19 19 28 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 0 0 0 0 0 0 0 55 0 0 0 55 0 % G
% His: 0 0 0 0 10 0 0 0 0 10 0 0 82 0 0 % H
% Ile: 0 0 10 10 10 0 0 10 0 10 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 82 0 55 55 55 10 73 0 82 10 82 10 0 10 82 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 0 % R
% Ser: 10 0 0 0 0 10 0 0 0 10 0 0 0 10 0 % S
% Thr: 0 0 0 0 0 73 0 0 0 0 0 10 19 0 0 % T
% Val: 0 10 10 0 0 10 10 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 73 10 0 10 0 0 19 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _