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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHDC8B
All Species:
32.12
Human Site:
T139
Identified Species:
78.52
UniProt:
Q8IXV7
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXV7
NP_775817.1
354
37676
T139
L
G
G
M
G
P
D
T
A
P
Q
A
Q
V
R
Chimpanzee
Pan troglodytes
XP_526201
354
37630
T139
L
G
G
M
G
P
D
T
A
P
Q
A
Q
V
R
Rhesus Macaque
Macaca mulatta
XP_001109561
354
37605
T139
L
G
G
M
G
P
D
T
A
P
Q
A
Q
V
C
Dog
Lupus familis
XP_541887
354
37591
T139
L
G
G
M
G
P
D
T
A
P
Q
A
Q
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2D9
354
37574
T139
L
G
G
M
G
P
D
T
A
P
Q
A
Q
V
L
Rat
Rattus norvegicus
Q5XIA9
354
37575
T139
L
G
G
M
G
P
D
T
A
P
Q
A
Q
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506477
359
38700
T144
L
G
G
M
G
S
D
T
A
P
Q
A
L
V
R
Chicken
Gallus gallus
XP_414393
354
37543
T139
L
G
G
M
G
A
D
T
S
P
Q
A
L
V
R
Frog
Xenopus laevis
NP_001085780
350
38644
L139
A
G
G
M
G
S
D
L
R
P
H
C
F
L
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789836
374
40439
T148
I
G
G
M
K
A
N
T
S
A
L
Q
L
C
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.7
96.6
N.A.
97.7
97.4
N.A.
74.6
68.9
45.7
N.A.
N.A.
N.A.
N.A.
N.A.
33.4
Protein Similarity:
100
100
99.7
98
N.A.
98.3
98.3
N.A.
83.5
77.9
64.9
N.A.
N.A.
N.A.
N.A.
N.A.
46.5
P-Site Identity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
86.6
80
40
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
86.6
86.6
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
20
0
0
70
10
0
80
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
10
% C
% Asp:
0
0
0
0
0
0
90
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
100
100
0
90
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
80
0
0
0
0
0
0
10
0
0
10
0
30
10
20
% L
% Met:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
60
0
0
0
90
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
80
10
60
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
60
% R
% Ser:
0
0
0
0
0
20
0
0
20
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
90
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
80
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _