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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHDC8B
All Species:
36.97
Human Site:
Y166
Identified Species:
90.37
UniProt:
Q8IXV7
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXV7
NP_775817.1
354
37676
Y166
P
S
M
P
T
P
C
Y
G
A
S
T
F
L
H
Chimpanzee
Pan troglodytes
XP_526201
354
37630
Y166
P
S
M
P
T
P
C
Y
G
A
S
T
F
L
H
Rhesus Macaque
Macaca mulatta
XP_001109561
354
37605
Y166
P
S
M
P
T
P
C
Y
G
A
S
T
F
L
H
Dog
Lupus familis
XP_541887
354
37591
Y166
P
S
M
P
T
P
C
Y
G
A
S
T
F
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2D9
354
37574
Y166
P
S
M
P
T
P
C
Y
G
A
S
T
F
L
H
Rat
Rattus norvegicus
Q5XIA9
354
37575
Y166
P
S
M
P
T
P
C
Y
G
A
S
T
F
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506477
359
38700
Y171
P
S
M
P
T
P
C
Y
G
A
S
T
F
L
Q
Chicken
Gallus gallus
XP_414393
354
37543
Y166
P
S
M
P
T
P
C
Y
G
A
S
A
F
L
Q
Frog
Xenopus laevis
NP_001085780
350
38644
Y166
A
P
M
P
T
P
R
Y
G
A
T
S
F
L
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789836
374
40439
Y175
P
D
M
P
T
A
R
Y
G
A
A
A
H
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.7
96.6
N.A.
97.7
97.4
N.A.
74.6
68.9
45.7
N.A.
N.A.
N.A.
N.A.
N.A.
33.4
Protein Similarity:
100
100
99.7
98
N.A.
98.3
98.3
N.A.
83.5
77.9
64.9
N.A.
N.A.
N.A.
N.A.
N.A.
46.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
86.6
60
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
86.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
0
0
100
10
20
0
0
0
% A
% Cys:
0
0
0
0
0
0
80
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
90
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
60
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
90
0
% L
% Met:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
90
10
0
100
0
90
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% Q
% Arg:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
10
% R
% Ser:
0
80
0
0
0
0
0
0
0
0
80
10
0
0
0
% S
% Thr:
0
0
0
0
100
0
0
0
0
0
10
70
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _