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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPAP2
All Species:
13.64
Human Site:
S186
Identified Species:
27.27
UniProt:
Q8IXW5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXW5
NP_079089.2
612
69509
S186
G
E
E
V
Q
L
C
S
K
A
I
K
T
S
D
Chimpanzee
Pan troglodytes
XP_001153375
612
69504
S186
G
E
E
V
Q
L
C
S
K
A
I
K
T
S
D
Rhesus Macaque
Macaca mulatta
XP_001099182
612
69551
S186
G
E
E
V
Q
L
C
S
K
A
I
K
T
S
D
Dog
Lupus familis
XP_541262
611
69140
T186
G
K
E
V
Q
L
C
T
K
A
I
K
T
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC34
614
68511
R186
G
E
V
V
Q
F
F
R
D
A
V
T
A
A
D
Rat
Rattus norvegicus
Q5I0E6
609
67874
R186
G
E
V
V
Q
F
F
R
D
A
V
T
A
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520901
401
44240
Chicken
Gallus gallus
XP_422341
614
68805
D181
G
E
E
V
K
L
C
D
E
V
I
K
A
S
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001019603
324
36817
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120766
239
28043
Nematode Worm
Caenorhab. elegans
P30641
455
52420
L34
D
I
E
N
T
D
Q
L
Q
E
H
L
P
H
L
Sea Urchin
Strong. purpuratus
XP_001198968
271
30853
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97
85.1
N.A.
70.1
69.2
N.A.
36.7
57.3
N.A.
28.2
N.A.
N.A.
21.5
20.9
22.7
Protein Similarity:
100
99.6
98.1
91.1
N.A.
80.4
80.8
N.A.
47
72.6
N.A.
39.8
N.A.
N.A.
30.3
36.2
32.3
P-Site Identity:
100
100
100
86.6
N.A.
40
40
N.A.
0
66.6
N.A.
0
N.A.
N.A.
0
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
53.3
53.3
N.A.
0
80
N.A.
0
N.A.
N.A.
0
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
50
0
0
25
17
0
% A
% Cys:
0
0
0
0
0
0
42
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
9
0
9
17
0
0
0
0
0
59
% D
% Glu:
0
50
50
0
0
0
0
0
9
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
17
17
0
0
0
0
0
0
0
0
% F
% Gly:
59
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
9
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
42
0
0
0
0
% I
% Lys:
0
9
0
0
9
0
0
0
34
0
0
42
0
0
0
% K
% Leu:
0
0
0
0
0
42
0
9
0
0
0
9
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
0
0
50
0
9
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
25
0
0
0
0
0
42
0
% S
% Thr:
0
0
0
0
9
0
0
9
0
0
0
17
34
0
0
% T
% Val:
0
0
17
59
0
0
0
0
0
9
17
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _