KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM183A
All Species:
16.06
Human Site:
S219
Identified Species:
44.17
UniProt:
Q8IXX5
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXX5
NP_612400.3
376
42826
S219
E
P
F
A
A
R
I
S
K
N
P
A
I
P
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537117
376
42773
S219
E
P
F
A
A
R
I
S
K
N
P
A
I
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJB9
375
42927
S218
E
P
F
A
A
R
I
S
K
N
P
A
I
P
E
Rat
Rattus norvegicus
Q68FS7
376
42963
S219
E
P
F
A
A
R
I
S
K
N
P
A
I
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521516
353
40327
K210
E
I
T
P
S
I
L
K
N
S
K
C
L
L
F
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001014317
364
41552
S211
K
S
P
P
L
P
E
S
T
P
T
T
L
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392998
225
26552
S83
D
S
N
K
S
K
K
S
T
K
G
V
L
T
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188636
392
45277
N219
E
P
Y
R
L
A
L
N
V
T
S
P
V
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001168843
236
26265
L94
V
G
E
P
S
D
I
L
D
S
S
D
E
M
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
97
N.A.
93.3
94.6
N.A.
85.6
N.A.
N.A.
64
N.A.
N.A.
21.5
N.A.
25.5
Protein Similarity:
100
N.A.
N.A.
98.6
N.A.
95.4
96.5
N.A.
89
N.A.
N.A.
76
N.A.
N.A.
36.4
N.A.
42.6
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
6.6
N.A.
N.A.
6.6
N.A.
N.A.
6.6
N.A.
20
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
33.3
N.A.
N.A.
20
N.A.
N.A.
33.3
N.A.
46.6
Percent
Protein Identity:
N.A.
59.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
60.6
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
45
45
12
0
0
0
0
0
45
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% C
% Asp:
12
0
0
0
0
12
0
0
12
0
0
12
0
0
12
% D
% Glu:
67
0
12
0
0
0
12
0
0
0
0
0
12
0
56
% E
% Phe:
0
0
45
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
12
0
0
0
0
0
0
0
0
12
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
12
56
0
0
0
0
0
45
0
0
% I
% Lys:
12
0
0
12
0
12
12
12
45
12
12
0
0
0
0
% K
% Leu:
0
0
0
0
23
0
23
12
0
0
0
0
34
23
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% M
% Asn:
0
0
12
0
0
0
0
12
12
45
0
0
0
0
23
% N
% Pro:
0
56
12
34
0
12
0
0
0
12
45
12
0
45
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
12
0
45
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
23
0
0
34
0
0
67
0
23
23
0
0
0
0
% S
% Thr:
0
0
12
0
0
0
0
0
23
12
12
12
0
12
0
% T
% Val:
12
0
0
0
0
0
0
0
12
0
0
12
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _