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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM183A
All Species:
14.55
Human Site:
Y133
Identified Species:
40
UniProt:
Q8IXX5
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXX5
NP_612400.3
376
42826
Y133
D
G
A
G
G
E
E
Y
P
M
D
I
W
L
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537117
376
42773
Y133
D
G
A
G
G
E
E
Y
P
M
D
I
W
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJB9
375
42927
Y132
P
D
G
T
G
E
E
Y
P
M
D
I
W
L
L
Rat
Rattus norvegicus
Q68FS7
376
42963
Y133
D
G
A
G
G
E
E
Y
P
M
D
I
W
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521516
353
40327
P124
L
L
A
A
Y
I
R
P
E
D
I
V
K
F
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001014317
364
41552
L125
P
I
D
I
W
L
V
L
A
A
Y
I
R
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392998
225
26552
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188636
392
45277
Y133
A
H
E
G
T
R
V
Y
P
T
D
L
W
Y
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001168843
236
26265
L8
M
A
R
G
P
G
Q
L
S
G
P
R
P
D
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
97
N.A.
93.3
94.6
N.A.
85.6
N.A.
N.A.
64
N.A.
N.A.
21.5
N.A.
25.5
Protein Similarity:
100
N.A.
N.A.
98.6
N.A.
95.4
96.5
N.A.
89
N.A.
N.A.
76
N.A.
N.A.
36.4
N.A.
42.6
P-Site Identity:
100
N.A.
N.A.
100
N.A.
73.3
100
N.A.
6.6
N.A.
N.A.
6.6
N.A.
N.A.
0
N.A.
33.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
73.3
100
N.A.
13.3
N.A.
N.A.
6.6
N.A.
N.A.
0
N.A.
46.6
Percent
Protein Identity:
N.A.
59.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
60.6
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
45
12
0
0
0
0
12
12
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
34
12
12
0
0
0
0
0
0
12
56
0
0
12
0
% D
% Glu:
0
0
12
0
0
45
45
0
12
0
0
0
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% F
% Gly:
0
34
12
56
45
12
0
0
0
12
0
0
0
0
0
% G
% His:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
12
0
12
0
0
0
0
12
56
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% K
% Leu:
12
12
0
0
0
12
0
23
0
0
0
12
0
45
45
% L
% Met:
12
0
0
0
0
0
0
0
0
45
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
23
0
0
0
12
0
0
12
56
0
12
0
12
12
0
% P
% Gln:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
12
0
0
12
12
0
0
0
0
12
12
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
12
% S
% Thr:
0
0
0
12
12
0
0
0
0
12
0
0
0
0
12
% T
% Val:
0
0
0
0
0
0
23
0
0
0
0
12
0
0
12
% V
% Trp:
0
0
0
0
12
0
0
0
0
0
0
0
56
0
0
% W
% Tyr:
0
0
0
0
12
0
0
56
0
0
12
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _