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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPIL6
All Species:
10.91
Human Site:
S185
Identified Species:
21.82
UniProt:
Q8IXY8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXY8
NP_001104768.1
311
35228
S185
C
T
G
K
A
G
F
S
Q
R
G
I
R
L
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090689
311
35243
S185
C
T
G
K
A
G
F
S
Q
R
G
I
R
L
H
Dog
Lupus familis
XP_855073
279
31955
H160
S
Q
S
G
I
K
L
H
Y
V
G
S
V
I
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9D6D8
278
31850
R159
I
D
L
S
P
I
G
R
L
I
F
E
L
Y
C
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518381
150
16559
A29
D
I
A
I
Q
D
E
A
I
G
R
L
V
F
E
Chicken
Gallus gallus
XP_419794
231
25674
L112
S
P
S
S
G
Q
E
L
T
Y
K
N
S
C
F
Frog
Xenopus laevis
NP_001088675
305
34296
T178
C
T
G
A
A
G
M
T
L
G
G
L
K
L
H
Zebra Danio
Brachydanio rerio
NP_001018433
293
32959
S166
C
T
G
E
A
G
L
S
K
S
N
L
E
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52011
173
18532
H54
G
K
S
G
K
P
L
H
F
K
G
S
K
F
H
Sea Urchin
Strong. purpuratus
XP_792119
260
29894
L141
D
G
E
K
I
G
R
L
L
F
E
L
F
T
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P21569
172
18330
L53
V
G
K
S
G
K
P
L
H
Y
K
G
S
T
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SKQ0
174
18445
H55
G
R
S
G
K
P
L
H
F
K
G
S
S
F
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.1
70
N.A.
59.8
N.A.
N.A.
36.3
48.5
58.8
54.6
N.A.
N.A.
N.A.
27.9
43.4
Protein Similarity:
100
N.A.
98.3
79
N.A.
72.9
N.A.
N.A.
40.1
57.2
71.6
65.5
N.A.
N.A.
N.A.
36.3
59.8
P-Site Identity:
100
N.A.
100
13.3
N.A.
0
N.A.
N.A.
0
0
53.3
46.6
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
100
N.A.
100
20
N.A.
0
N.A.
N.A.
13.3
0
73.3
66.6
N.A.
N.A.
N.A.
26.6
20
Percent
Protein Identity:
N.A.
27.9
N.A.
25.7
N.A.
N.A.
Protein Similarity:
N.A.
36.3
N.A.
35.3
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
0
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
34
0
0
9
0
0
0
0
0
0
0
% A
% Cys:
34
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% C
% Asp:
17
9
0
0
0
9
0
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
9
9
0
0
17
0
0
0
9
9
9
0
9
% E
% Phe:
0
0
0
0
0
0
17
0
17
9
9
0
9
25
17
% F
% Gly:
17
17
34
25
17
42
9
0
0
17
50
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
25
9
0
0
0
0
0
50
% H
% Ile:
9
9
0
9
17
9
0
0
9
9
0
17
0
9
0
% I
% Lys:
0
9
9
25
17
17
0
0
9
17
17
0
17
0
0
% K
% Leu:
0
0
9
0
0
0
34
25
25
0
0
34
9
34
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% N
% Pro:
0
9
0
0
9
17
9
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
9
9
0
0
17
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
0
9
9
0
17
9
0
17
0
0
% R
% Ser:
17
0
34
25
0
0
0
25
0
9
0
25
25
0
9
% S
% Thr:
0
34
0
0
0
0
0
9
9
0
0
0
0
17
0
% T
% Val:
9
0
0
0
0
0
0
0
0
9
0
0
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
17
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _