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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPIL6
All Species:
14.55
Human Site:
T227
Identified Species:
29.09
UniProt:
Q8IXY8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.55
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXY8
NP_001104768.1
311
35228
T227
G
E
S
I
Y
G
P
T
F
E
D
E
N
F
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090689
311
35243
T227
G
E
S
I
Y
G
P
T
F
E
D
E
N
F
S
Dog
Lupus familis
XP_855073
279
31955
E199
Y
G
P
T
F
E
D
E
N
F
S
I
P
H
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9D6D8
278
31850
S198
T
K
L
H
Y
K
D
S
I
F
H
R
V
V
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518381
150
16559
Y68
P
S
G
V
R
L
H
Y
K
D
S
A
F
H
R
Chicken
Gallus gallus
XP_419794
231
25674
E151
Y
G
P
T
F
E
D
E
N
Y
A
I
P
H
K
Frog
Xenopus laevis
NP_001088675
305
34296
T220
G
E
S
I
F
G
E
T
F
E
D
E
N
F
A
Zebra Danio
Brachydanio rerio
NP_001018433
293
32959
T209
G
E
S
I
Y
G
P
T
F
E
D
E
N
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52011
173
18532
E93
Y
G
E
K
F
P
D
E
N
F
K
E
K
H
T
Sea Urchin
Strong. purpuratus
XP_792119
260
29894
E180
L
M
K
F
H
Y
L
E
S
L
F
H
R
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P21569
172
18330
D92
I
Y
G
E
K
F
P
D
E
K
F
V
R
K
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SKQ0
174
18445
E94
Y
G
A
K
F
E
D
E
N
F
E
R
K
H
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.1
70
N.A.
59.8
N.A.
N.A.
36.3
48.5
58.8
54.6
N.A.
N.A.
N.A.
27.9
43.4
Protein Similarity:
100
N.A.
98.3
79
N.A.
72.9
N.A.
N.A.
40.1
57.2
71.6
65.5
N.A.
N.A.
N.A.
36.3
59.8
P-Site Identity:
100
N.A.
100
0
N.A.
6.6
N.A.
N.A.
0
0
80
93.3
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
N.A.
100
13.3
N.A.
20
N.A.
N.A.
13.3
6.6
93.3
93.3
N.A.
N.A.
N.A.
20
6.6
Percent
Protein Identity:
N.A.
27.9
N.A.
25.7
N.A.
N.A.
Protein Similarity:
N.A.
36.3
N.A.
35.3
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
0
0
9
9
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
42
9
0
9
34
0
0
0
0
% D
% Glu:
0
34
9
9
0
25
9
42
9
34
9
42
0
0
0
% E
% Phe:
0
0
0
9
42
9
0
0
34
34
17
0
9
34
0
% F
% Gly:
34
34
17
0
0
34
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
9
9
0
9
0
0
0
9
9
0
42
0
% H
% Ile:
9
0
0
34
0
0
0
0
9
0
0
17
0
9
0
% I
% Lys:
0
9
9
17
9
9
0
0
9
9
9
0
17
9
9
% K
% Leu:
9
0
9
0
0
9
9
0
0
9
0
0
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
34
0
0
0
34
0
9
% N
% Pro:
9
0
17
0
0
9
34
0
0
0
0
0
17
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% Q
% Arg:
0
0
0
0
9
0
0
0
0
0
0
17
17
0
9
% R
% Ser:
0
9
34
0
0
0
0
9
9
0
17
0
0
0
17
% S
% Thr:
9
0
0
17
0
0
0
34
0
0
0
0
0
0
17
% T
% Val:
0
0
0
9
0
0
0
0
0
0
0
9
9
9
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
34
9
0
0
34
9
0
9
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _