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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZC3H3
All Species:
8.18
Human Site:
S911
Identified Species:
16.36
UniProt:
Q8IXZ2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXZ2
NP_055932.2
948
101930
S911
N
R
L
C
K
L
P
S
F
I
S
L
Q
S
S
Chimpanzee
Pan troglodytes
XP_519998
1257
135558
C1216
A
A
C
S
N
R
L
C
K
L
P
S
F
I
S
Rhesus Macaque
Macaca mulatta
XP_001097060
1074
115065
S1037
N
R
L
C
K
L
P
S
F
I
S
L
Q
S
S
Dog
Lupus familis
XP_539198
1016
109897
P975
L
Q
E
E
A
A
S
P
A
T
G
S
G
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHP0
950
103206
L906
S
G
T
G
S
S
G
L
C
K
L
P
S
F
I
Rat
Rattus norvegicus
NP_001128337
952
103496
S915
G
S
L
C
K
L
P
S
F
I
S
L
H
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518934
951
103158
H894
G
E
K
C
K
K
K
H
T
L
L
C
P
D
F
Chicken
Gallus gallus
NP_001026756
956
105809
D912
C
K
V
E
R
D
E
D
E
P
M
D
E
P
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689680
929
101372
D893
P
D
G
S
E
N
P
D
T
P
K
I
P
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648230
597
66304
A563
V
E
Q
K
K
P
E
A
E
D
E
D
Q
K
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785788
1142
125989
F1097
A
L
K
I
R
P
L
F
A
P
S
M
G
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q3ED78
470
53750
E436
T
L
G
T
A
E
Y
E
A
G
D
D
N
D
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.8
82.8
70.8
N.A.
70.6
70.6
N.A.
47.7
42.4
N.A.
36.3
N.A.
22.4
N.A.
N.A.
25.6
Protein Similarity:
100
74.4
84.3
77.9
N.A.
79.5
79.3
N.A.
57.2
56.2
N.A.
52
N.A.
37.2
N.A.
N.A.
38.7
P-Site Identity:
100
6.6
100
6.6
N.A.
0
80
N.A.
13.3
0
N.A.
6.6
N.A.
13.3
N.A.
N.A.
13.3
P-Site Similarity:
100
13.3
100
13.3
N.A.
6.6
80
N.A.
20
26.6
N.A.
26.6
N.A.
20
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
0
0
17
9
0
9
25
0
0
0
0
9
9
% A
% Cys:
9
0
9
34
0
0
0
9
9
0
0
9
0
0
0
% C
% Asp:
0
9
0
0
0
9
0
17
0
9
9
25
0
17
0
% D
% Glu:
0
17
9
17
9
9
17
9
17
0
9
0
9
0
9
% E
% Phe:
0
0
0
0
0
0
0
9
25
0
0
0
9
9
9
% F
% Gly:
17
9
17
9
0
0
9
0
0
9
9
0
17
0
9
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
25
0
9
0
9
9
% I
% Lys:
0
9
17
9
42
9
9
0
9
9
9
0
0
9
0
% K
% Leu:
9
17
25
0
0
25
17
9
0
17
17
25
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% M
% Asn:
17
0
0
0
9
9
0
0
0
0
0
0
9
0
0
% N
% Pro:
9
0
0
0
0
17
34
9
0
25
9
9
17
17
9
% P
% Gln:
0
9
9
0
0
0
0
0
0
0
0
0
25
0
0
% Q
% Arg:
0
17
0
0
17
9
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
9
0
17
9
9
9
25
0
0
34
17
9
34
42
% S
% Thr:
9
0
9
9
0
0
0
0
17
9
0
0
0
0
0
% T
% Val:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _