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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZC3H3
All Species:
23.94
Human Site:
Y377
Identified Species:
47.88
UniProt:
Q8IXZ2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXZ2
NP_055932.2
948
101930
Y377
P
G
S
A
P
S
K
Y
K
W
K
A
S
S
P
Chimpanzee
Pan troglodytes
XP_519998
1257
135558
Y682
P
G
S
A
P
S
K
Y
K
W
K
A
S
S
P
Rhesus Macaque
Macaca mulatta
XP_001097060
1074
115065
Y505
P
G
S
A
P
S
K
Y
K
W
K
A
S
S
P
Dog
Lupus familis
XP_539198
1016
109897
Y441
P
G
A
S
P
S
K
Y
K
W
K
A
S
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHP0
950
103206
Y374
P
G
L
S
P
S
K
Y
K
W
K
A
S
S
P
Rat
Rattus norvegicus
NP_001128337
952
103496
Y375
A
G
A
S
P
S
K
Y
K
W
K
A
S
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518934
951
103158
P368
G
K
A
G
P
P
V
P
D
A
L
R
L
Q
R
Chicken
Gallus gallus
NP_001026756
956
105809
A387
K
S
G
L
Q
S
K
A
G
V
S
P
S
K
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689680
929
101372
K352
C
S
L
S
T
A
G
K
A
N
P
S
V
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648230
597
66304
F40
Q
L
P
F
Q
V
P
F
Q
A
F
Q
A
P
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785788
1142
125989
Y545
C
D
L
K
I
S
R
Y
K
L
V
K
S
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q3ED78
470
53750
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.8
82.8
70.8
N.A.
70.6
70.6
N.A.
47.7
42.4
N.A.
36.3
N.A.
22.4
N.A.
N.A.
25.6
Protein Similarity:
100
74.4
84.3
77.9
N.A.
79.5
79.3
N.A.
57.2
56.2
N.A.
52
N.A.
37.2
N.A.
N.A.
38.7
P-Site Identity:
100
100
100
86.6
N.A.
86.6
80
N.A.
6.6
20
N.A.
0
N.A.
0
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
13.3
20
N.A.
20
N.A.
20
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
25
25
0
9
0
9
9
17
0
50
9
0
0
% A
% Cys:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
9
0
0
9
0
0
0
0
% F
% Gly:
9
50
9
9
0
0
9
0
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
9
0
9
0
0
59
9
59
0
50
9
0
17
0
% K
% Leu:
0
9
25
9
0
0
0
0
0
9
9
0
9
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
42
0
9
0
59
9
9
9
0
0
9
9
0
9
50
% P
% Gln:
9
0
0
0
17
0
0
0
9
0
0
9
0
9
0
% Q
% Arg:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
9
% R
% Ser:
0
17
25
34
0
67
0
0
0
0
9
9
67
59
9
% S
% Thr:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
9
9
0
0
9
9
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
59
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _