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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SP8
All Species:
5.45
Human Site:
S457
Identified Species:
13.33
UniProt:
Q8IXZ3
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXZ3
NP_874359.2
508
50500
S457
S
K
H
V
K
T
H
S
G
G
G
G
G
G
G
Chimpanzee
Pan troglodytes
Q19A40
323
33082
H281
A
R
R
H
P
T
Y
H
P
D
M
I
E
Y
R
Rhesus Macaque
Macaca mulatta
XP_001102781
508
50467
H457
L
S
K
H
V
K
T
H
S
G
G
G
G
G
G
Dog
Lupus familis
XP_853680
395
41054
A353
G
G
G
G
G
G
S
A
G
S
G
S
G
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMJ8
486
48399
S444
T
H
S
G
G
G
G
S
A
G
S
G
G
G
K
Rat
Rattus norvegicus
Q01714
786
80753
Q710
S
K
H
I
K
T
H
Q
N
K
K
G
G
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90WR8
771
80932
Q694
A
K
H
I
K
T
H
Q
N
K
K
G
I
H
S
Frog
Xenopus laevis
NP_001088307
500
49213
S452
S
K
H
V
K
T
H
S
V
G
G
G
S
T
G
Zebra Danio
Brachydanio rerio
NP_991113
437
45681
K395
G
S
G
A
S
G
G
K
R
G
S
D
T
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001096927
715
72838
N468
A
K
H
V
K
T
H
N
G
T
A
N
H
Q
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.1
99.4
65.5
N.A.
93.9
27.1
N.A.
N.A.
27.3
71.6
69.8
N.A.
29.6
N.A.
N.A.
N.A.
Protein Similarity:
100
37
99.6
68.9
N.A.
94.2
38.4
N.A.
N.A.
38.2
77.9
76.1
N.A.
39.1
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
40
26.6
N.A.
33.3
60
N.A.
N.A.
40
80
6.6
N.A.
46.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
40
33.3
N.A.
40
66.6
N.A.
N.A.
53.3
80
6.6
N.A.
60
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
0
0
10
0
0
0
10
10
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
10
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
20
10
20
20
20
30
20
0
30
50
40
60
50
40
40
% G
% His:
0
10
50
20
0
0
50
20
0
0
0
0
10
10
0
% H
% Ile:
0
0
0
20
0
0
0
0
0
0
0
10
10
0
0
% I
% Lys:
0
50
10
0
50
10
0
10
0
20
20
0
0
0
20
% K
% Leu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
20
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
10
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
20
0
0
0
0
0
10
0
% Q
% Arg:
0
10
10
0
0
0
0
0
10
0
0
0
0
0
10
% R
% Ser:
30
20
10
0
10
0
10
30
10
10
20
10
10
0
20
% S
% Thr:
10
0
0
0
0
60
10
0
0
10
0
0
10
10
0
% T
% Val:
0
0
0
30
10
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _