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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PNPLA6 All Species: 25.15
Human Site: S112 Identified Species: 50.3
UniProt: Q8IY17 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IY17 NP_006693.3 1366 149995 S112 K V S Q S T S S L V D T S V S
Chimpanzee Pan troglodytes XP_512331 1484 162976 S230 K V S Q S T S S L V D T S V S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_542111 1474 161798 S232 K V S Q S T S S L V D A S V S
Cat Felis silvestris
Mouse Mus musculus Q3TRM4 1355 149519 S105 K V S Q S T S S L V D T S V S
Rat Rattus norvegicus Q5BK26 1349 150006 T98 K V T T L P H T L V G N T A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001106924 1321 147821 S98 K V S Q S T S S L V D T T I S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921208 1348 150755 S98 K V S Q S T S S L V G A T S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U969 1425 160554 Q109 K M K N V S G Q M Y S S G K G
Honey Bee Apis mellifera XP_001120383 1324 149002 Q103 K V K S I S G Q V H A T G Q G
Nematode Worm Caenorhab. elegans Q02331 1353 152377 I103 T P T N T Q T I E P P T S L N
Sea Urchin Strong. purpuratus XP_001202094 1454 161991 S149 L D V I T V K S I S G P V Y T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7S8J1 1515 167542 G232 D G R R S S S G P S F E S D D
Conservation
Percent
Protein Identity: 100 89 N.A. 88.1 N.A. 94.3 59.2 N.A. N.A. 77.1 N.A. 71.2 N.A. 40 45.2 33.1 43.9
Protein Similarity: 100 89.7 N.A. 90.2 N.A. 96.1 71.5 N.A. N.A. 84.7 N.A. 81.7 N.A. 58.1 61.4 51 60.8
P-Site Identity: 100 100 N.A. 93.3 N.A. 100 26.6 N.A. N.A. 86.6 N.A. 73.3 N.A. 6.6 20 13.3 6.6
P-Site Similarity: 100 100 N.A. 93.3 N.A. 100 53.3 N.A. N.A. 100 N.A. 80 N.A. 33.3 33.3 46.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 28.7
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 45
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 20
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 9 17 0 9 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 9 0 0 0 0 0 0 0 0 42 0 0 9 9 % D
% Glu: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % F
% Gly: 0 9 0 0 0 0 17 9 0 0 25 0 17 0 17 % G
% His: 0 0 0 0 0 0 9 0 0 9 0 0 0 0 0 % H
% Ile: 0 0 0 9 9 0 0 9 9 0 0 0 0 9 0 % I
% Lys: 75 0 17 0 0 0 9 0 0 0 0 0 0 9 0 % K
% Leu: 9 0 0 0 9 0 0 0 59 0 0 0 0 9 0 % L
% Met: 0 9 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 17 0 0 0 0 0 0 0 9 0 0 9 % N
% Pro: 0 9 0 0 0 9 0 0 9 9 9 9 0 0 0 % P
% Gln: 0 0 0 50 0 9 0 17 0 0 0 0 0 9 0 % Q
% Arg: 0 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 50 9 59 25 59 59 0 17 9 9 50 9 50 % S
% Thr: 9 0 17 9 17 50 9 9 0 0 0 50 25 0 9 % T
% Val: 0 67 9 0 9 9 0 0 9 59 0 0 9 34 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 9 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _