Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PNPLA6 All Species: 9.7
Human Site: S1330 Identified Species: 19.39
UniProt: Q8IY17 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IY17 NP_006693.3 1366 149995 S1330 C S R D E G G S P E G A S P S
Chimpanzee Pan troglodytes XP_512331 1484 162976 S1448 C S R D E G G S P E G A S P S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_542111 1474 161798 G1437 D C S R D E G G S P E G A S P
Cat Felis silvestris
Mouse Mus musculus Q3TRM4 1355 149519 S1319 C S R D E G G S P E G A S P S
Rat Rattus norvegicus Q5BK26 1349 150006 L1305 F Q S T G I E L D S D S E C E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001106924 1321 147821 D1286 G Y A D E E S D Y L T E Y E D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921208 1348 150755 E1302 E G E E E E E E G E D P E D Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U969 1425 160554 G1310 R I Q V S R A G N S L S F S E
Honey Bee Apis mellifera XP_001120383 1324 149002 S1282 A Q E V G Y A S E P T A G I L
Nematode Worm Caenorhab. elegans Q02331 1353 152377 N1300 L L D D D L F N D T D Y Y E E
Sea Urchin Strong. purpuratus XP_001202094 1454 161991 E1379 I G T E S A S E M N P S S D V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7S8J1 1515 167542 K1467 Y G T L D F G K F D E I Y G V
Conservation
Percent
Protein Identity: 100 89 N.A. 88.1 N.A. 94.3 59.2 N.A. N.A. 77.1 N.A. 71.2 N.A. 40 45.2 33.1 43.9
Protein Similarity: 100 89.7 N.A. 90.2 N.A. 96.1 71.5 N.A. N.A. 84.7 N.A. 81.7 N.A. 58.1 61.4 51 60.8
P-Site Identity: 100 100 N.A. 6.6 N.A. 100 0 N.A. N.A. 13.3 N.A. 13.3 N.A. 0 13.3 6.6 6.6
P-Site Similarity: 100 100 N.A. 20 N.A. 100 6.6 N.A. N.A. 13.3 N.A. 20 N.A. 13.3 13.3 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 28.7
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 45
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 0 0 9 17 0 0 0 0 34 9 0 0 % A
% Cys: 25 9 0 0 0 0 0 0 0 0 0 0 0 9 0 % C
% Asp: 9 0 9 42 25 0 0 9 17 9 25 0 0 17 9 % D
% Glu: 9 0 17 17 42 25 17 17 9 34 17 9 17 17 25 % E
% Phe: 9 0 0 0 0 9 9 0 9 0 0 0 9 0 0 % F
% Gly: 9 25 0 0 17 25 42 17 9 0 25 9 9 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 9 0 0 0 9 0 0 0 0 0 9 0 9 0 % I
% Lys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % K
% Leu: 9 9 0 9 0 9 0 9 0 9 9 0 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 9 9 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 25 17 9 9 0 25 9 % P
% Gln: 0 17 9 0 0 0 0 0 0 0 0 0 0 0 9 % Q
% Arg: 9 0 25 9 0 9 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 25 17 0 17 0 17 34 9 17 0 25 34 17 25 % S
% Thr: 0 0 17 9 0 0 0 0 0 9 17 0 0 0 0 % T
% Val: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 9 0 0 0 9 0 0 9 0 0 9 25 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _