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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PNPLA6 All Species: 9.09
Human Site: S1337 Identified Species: 18.18
UniProt: Q8IY17 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IY17 NP_006693.3 1366 149995 S1337 S P E G A S P S T A S E M E E
Chimpanzee Pan troglodytes XP_512331 1484 162976 S1455 S P E G A S P S T A S E M E E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_542111 1474 161798 P1444 G S P E G A S P S T A S E M E
Cat Felis silvestris
Mouse Mus musculus Q3TRM4 1355 149519 S1326 S P E G A S P S T A S E V E E
Rat Rattus norvegicus Q5BK26 1349 150006 E1312 L D S D S E C E P S M S Q G P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001106924 1321 147821 D1293 D Y L T E Y E D E G P E L S R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921208 1348 150755 Q1309 E G E D P E D Q S P G E W G P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U969 1425 160554 E1317 G N S L S F S E T E M D S D V
Honey Bee Apis mellifera XP_001120383 1324 149002 L1289 S E P T A G I L D Q S P D E N
Nematode Worm Caenorhab. elegans Q02331 1353 152377 E1307 N D T D Y Y E E E S S Q S E N
Sea Urchin Strong. purpuratus XP_001202094 1454 161991 V1386 E M N P S S D V P N A T N S E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7S8J1 1515 167542 V1474 K F D E I Y G V G Y K Y G Q E
Conservation
Percent
Protein Identity: 100 89 N.A. 88.1 N.A. 94.3 59.2 N.A. N.A. 77.1 N.A. 71.2 N.A. 40 45.2 33.1 43.9
Protein Similarity: 100 89.7 N.A. 90.2 N.A. 96.1 71.5 N.A. N.A. 84.7 N.A. 81.7 N.A. 58.1 61.4 51 60.8
P-Site Identity: 100 100 N.A. 6.6 N.A. 93.3 0 N.A. N.A. 6.6 N.A. 13.3 N.A. 6.6 26.6 13.3 13.3
P-Site Similarity: 100 100 N.A. 26.6 N.A. 100 13.3 N.A. N.A. 13.3 N.A. 20 N.A. 26.6 26.6 33.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 28.7
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 45
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 34 9 0 0 0 25 17 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 9 17 9 25 0 0 17 9 9 0 0 9 9 9 0 % D
% Glu: 17 9 34 17 9 17 17 25 17 9 0 42 9 42 50 % E
% Phe: 0 9 0 0 0 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 17 9 0 25 9 9 9 0 9 9 9 0 9 17 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 0 9 0 0 0 0 0 0 0 0 % I
% Lys: 9 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % K
% Leu: 9 0 9 9 0 0 0 9 0 0 0 0 9 0 0 % L
% Met: 0 9 0 0 0 0 0 0 0 0 17 0 17 9 0 % M
% Asn: 9 9 9 0 0 0 0 0 0 9 0 0 9 0 17 % N
% Pro: 0 25 17 9 9 0 25 9 17 9 9 9 0 0 17 % P
% Gln: 0 0 0 0 0 0 0 9 0 9 0 9 9 9 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % R
% Ser: 34 9 17 0 25 34 17 25 17 17 42 17 17 17 0 % S
% Thr: 0 0 9 17 0 0 0 0 34 9 0 9 0 0 0 % T
% Val: 0 0 0 0 0 0 0 17 0 0 0 0 9 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % W
% Tyr: 0 9 0 0 9 25 0 0 0 9 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _