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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PNPLA6 All Species: 11.23
Human Site: S1362 Identified Species: 22.46
UniProt: Q8IY17 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IY17 NP_006693.3 1366 149995 S1362 L P Q E P P G S A T D A _ _ _
Chimpanzee Pan troglodytes XP_512331 1484 162976 S1480 L P Q E L P G S A T D A _ _ _
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_542111 1474 161798 T1469 C V P L E P P T T A A D A _ _
Cat Felis silvestris
Mouse Mus musculus Q3TRM4 1355 149519 S1351 L P Q E T P S S V A D A _ _ _
Rat Rattus norvegicus Q5BK26 1349 150006 N1337 D S F P W L P N Q D D Q G P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001106924 1321 147821
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921208 1348 150755 V1334 T V R Q R K N V S R D P N A D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U969 1425 160554 P1342 D K S T Q S S P P S N S R S D
Honey Bee Apis mellifera XP_001120383 1324 149002 E1314 S L S D T E A E S E L D Y H T
Nematode Worm Caenorhab. elegans Q02331 1353 152377 S1332 L V I G P P S S S S S G G N V
Sea Urchin Strong. purpuratus XP_001202094 1454 161991 S1411 T V I G S E I S S E D A S E D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7S8J1 1515 167542 E1499 L P L V E E T E A K K A L R R
Conservation
Percent
Protein Identity: 100 89 N.A. 88.1 N.A. 94.3 59.2 N.A. N.A. 77.1 N.A. 71.2 N.A. 40 45.2 33.1 43.9
Protein Similarity: 100 89.7 N.A. 90.2 N.A. 96.1 71.5 N.A. N.A. 84.7 N.A. 81.7 N.A. 58.1 61.4 51 60.8
P-Site Identity: 100 91.6 N.A. 7.6 N.A. 66.6 6.6 N.A. N.A. 0 N.A. 6.6 N.A. 0 0 26.6 20
P-Site Similarity: 100 91.6 N.A. 15.3 N.A. 66.6 20 N.A. N.A. 0 N.A. 26.6 N.A. 20 20 46.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 28.7
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 45
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 0 25 17 9 42 9 9 0 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 17 0 0 9 0 0 0 0 0 9 50 17 0 0 25 % D
% Glu: 0 0 0 25 17 25 0 17 0 17 0 0 0 9 0 % E
% Phe: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 17 0 0 17 0 0 0 0 9 17 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 17 0 0 0 9 0 0 0 0 0 0 0 0 % I
% Lys: 0 9 0 0 0 9 0 0 0 9 9 0 0 0 0 % K
% Leu: 42 9 9 9 9 9 0 0 0 0 9 0 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 9 9 0 0 9 0 9 9 0 % N
% Pro: 0 34 9 9 17 42 17 9 9 0 0 9 0 9 0 % P
% Gln: 0 0 25 9 9 0 0 0 9 0 0 9 0 0 0 % Q
% Arg: 0 0 9 0 9 0 0 0 0 9 0 0 9 9 17 % R
% Ser: 9 9 17 0 9 9 25 42 34 17 9 9 9 9 0 % S
% Thr: 17 0 0 9 17 0 9 9 9 17 0 0 0 0 9 % T
% Val: 0 34 0 9 0 0 0 9 9 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 25 34 34 % _