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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA6
All Species:
10.61
Human Site:
S353
Identified Species:
21.21
UniProt:
Q8IY17
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY17
NP_006693.3
1366
149995
S353
P
G
L
P
T
R
T
S
P
V
R
G
S
K
R
Chimpanzee
Pan troglodytes
XP_512331
1484
162976
S471
P
G
L
P
T
R
T
S
P
V
R
G
S
K
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542111
1474
161798
S473
P
G
L
P
S
R
T
S
P
V
R
G
S
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3TRM4
1355
149519
P347
G
L
P
T
R
T
S
P
V
R
G
S
K
R
V
Rat
Rattus norvegicus
Q5BK26
1349
150006
K337
A
S
V
A
G
R
A
K
R
Q
M
S
Y
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001106924
1321
147821
P325
L
F
S
H
E
M
Q
P
L
R
L
F
P
Q
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921208
1348
150755
P337
P
H
P
T
R
S
S
P
V
R
H
S
K
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U969
1425
160554
T341
S
G
P
I
N
S
Q
T
S
Q
S
S
R
Q
A
Honey Bee
Apis mellifera
XP_001120383
1324
149002
T302
R
L
Q
R
V
T
F
T
A
L
H
Q
Y
L
G
Nematode Worm
Caenorhab. elegans
Q02331
1353
152377
G311
V
K
C
I
P
A
G
G
S
F
F
S
L
L
S
Sea Urchin
Strong. purpuratus
XP_001202094
1454
161991
K394
R
L
D
N
I
S
S
K
S
L
A
I
H
A
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S8J1
1515
167542
G459
Q
L
P
N
H
L
R
G
D
A
L
D
R
L
K
Conservation
Percent
Protein Identity:
100
89
N.A.
88.1
N.A.
94.3
59.2
N.A.
N.A.
77.1
N.A.
71.2
N.A.
40
45.2
33.1
43.9
Protein Similarity:
100
89.7
N.A.
90.2
N.A.
96.1
71.5
N.A.
N.A.
84.7
N.A.
81.7
N.A.
58.1
61.4
51
60.8
P-Site Identity:
100
100
N.A.
93.3
N.A.
0
6.6
N.A.
N.A.
0
N.A.
6.6
N.A.
6.6
0
0
0
P-Site Similarity:
100
100
N.A.
100
N.A.
13.3
13.3
N.A.
N.A.
6.6
N.A.
20
N.A.
20
13.3
0
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
28.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
45
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
0
9
9
0
9
9
9
0
0
9
9
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
0
0
9
0
0
9
0
0
0
% D
% Glu:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
9
0
0
9
9
9
0
0
9
% F
% Gly:
9
34
0
0
9
0
9
17
0
0
9
25
0
9
9
% G
% His:
0
9
0
9
9
0
0
0
0
0
17
0
9
0
0
% H
% Ile:
0
0
0
17
9
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
0
9
0
0
0
0
0
17
0
0
0
0
17
25
9
% K
% Leu:
9
34
25
0
0
9
0
0
9
17
17
0
9
25
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
9
% M
% Asn:
0
0
0
17
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
34
0
34
25
9
0
0
25
25
0
0
0
9
0
17
% P
% Gln:
9
0
9
0
0
0
17
0
0
17
0
9
0
17
0
% Q
% Arg:
17
0
0
9
17
34
9
0
9
25
25
0
17
17
25
% R
% Ser:
9
9
9
0
9
25
25
25
25
0
9
42
25
0
9
% S
% Thr:
0
0
0
17
17
17
25
17
0
0
0
0
0
0
0
% T
% Val:
9
0
9
0
9
0
0
0
17
25
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _