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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPLA6
All Species:
16.67
Human Site:
S417
Identified Species:
33.33
UniProt:
Q8IY17
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY17
NP_006693.3
1366
149995
S417
V
S
M
P
G
D
I
S
G
L
Q
G
G
P
R
Chimpanzee
Pan troglodytes
XP_512331
1484
162976
S535
V
S
M
P
G
D
I
S
G
L
Q
G
G
P
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542111
1474
161798
S537
I
S
M
P
V
D
I
S
D
F
D
M
A
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3TRM4
1355
149519
S411
I
S
M
P
V
D
I
S
G
L
Q
G
G
P
R
Rat
Rattus norvegicus
Q5BK26
1349
150006
S401
Q
G
S
G
S
N
T
S
A
F
Q
E
S
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001106924
1321
147821
S389
I
S
M
P
V
D
I
S
G
I
Q
K
G
P
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921208
1348
150755
R401
D
F
D
M
A
Y
E
R
G
R
I
S
V
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U969
1425
160554
S405
P
N
P
N
P
D
G
S
F
H
G
T
T
N
L
Honey Bee
Apis mellifera
XP_001120383
1324
149002
H366
H
D
K
N
E
I
V
H
I
S
T
L
S
S
H
Nematode Worm
Caenorhab. elegans
Q02331
1353
152377
H375
I
V
I
T
R
L
L
H
V
T
L
T
T
L
H
Sea Urchin
Strong. purpuratus
XP_001202094
1454
161991
G458
F
K
S
A
R
V
L
G
P
I
S
N
W
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S8J1
1515
167542
P523
Q
S
I
V
T
A
T
P
A
F
G
T
R
R
E
Conservation
Percent
Protein Identity:
100
89
N.A.
88.1
N.A.
94.3
59.2
N.A.
N.A.
77.1
N.A.
71.2
N.A.
40
45.2
33.1
43.9
Protein Similarity:
100
89.7
N.A.
90.2
N.A.
96.1
71.5
N.A.
N.A.
84.7
N.A.
81.7
N.A.
58.1
61.4
51
60.8
P-Site Identity:
100
100
N.A.
40
N.A.
86.6
13.3
N.A.
N.A.
73.3
N.A.
6.6
N.A.
13.3
0
0
6.6
P-Site Similarity:
100
100
N.A.
46.6
N.A.
93.3
20
N.A.
N.A.
86.6
N.A.
6.6
N.A.
20
6.6
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
28.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
45
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
9
0
0
17
0
0
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
9
0
0
50
0
0
9
0
9
0
0
0
0
% D
% Glu:
0
0
0
0
9
0
9
0
0
0
0
9
0
0
25
% E
% Phe:
9
9
0
0
0
0
0
0
9
25
0
0
0
0
0
% F
% Gly:
0
9
0
9
17
0
9
9
42
0
17
25
34
0
0
% G
% His:
9
0
0
0
0
0
0
17
0
9
0
0
0
0
17
% H
% Ile:
34
0
17
0
0
9
42
0
9
17
9
0
0
0
0
% I
% Lys:
0
9
9
0
0
0
0
0
0
0
0
9
0
0
0
% K
% Leu:
0
0
0
0
0
9
17
0
0
25
9
9
0
9
9
% L
% Met:
0
0
42
9
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
9
0
17
0
9
0
0
0
0
0
9
0
9
0
% N
% Pro:
9
0
9
42
9
0
0
9
9
0
0
0
0
34
0
% P
% Gln:
17
0
0
0
0
0
0
0
0
0
42
0
0
9
0
% Q
% Arg:
0
0
0
0
17
0
0
9
0
9
0
0
9
17
42
% R
% Ser:
0
50
17
0
9
0
0
59
0
9
9
9
17
17
0
% S
% Thr:
0
0
0
9
9
0
17
0
0
9
9
25
17
0
0
% T
% Val:
17
9
0
9
25
9
9
0
9
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _