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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PNPLA6 All Species: 39.09
Human Site: S933 Identified Species: 78.18
UniProt: Q8IY17 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IY17 NP_006693.3 1366 149995 S933 R C P R R L F S R R S P A K L
Chimpanzee Pan troglodytes XP_512331 1484 162976 S1051 R C P R R L F S R R S P A K L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_542111 1474 161798 S1040 R C P R R L F S R R S P A K L
Cat Felis silvestris
Mouse Mus musculus Q3TRM4 1355 149519 S922 R C P R R L F S R R S P A K L
Rat Rattus norvegicus Q5BK26 1349 150006 S908 C C P R R V F S K R S L P K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001106924 1321 147821 S910 K C P R R V F S R R S P A K L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921208 1348 150755 S905 K C P R R V F S R R S P T K L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U969 1425 160554 T913 L C V K R I F T R K S Q Y R I
Honey Bee Apis mellifera XP_001120383 1324 149002 T885 Q C P K R M F T R R S Q Y R I
Nematode Worm Caenorhab. elegans Q02331 1353 152377 P903 S R A E V M T P T S V E N E V
Sea Urchin Strong. purpuratus XP_001202094 1454 161991 S982 R C P K R M F S K R S P A R V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7S8J1 1515 167542 T1070 T N V N T P W T Q T C I T Q A
Conservation
Percent
Protein Identity: 100 89 N.A. 88.1 N.A. 94.3 59.2 N.A. N.A. 77.1 N.A. 71.2 N.A. 40 45.2 33.1 43.9
Protein Similarity: 100 89.7 N.A. 90.2 N.A. 96.1 71.5 N.A. N.A. 84.7 N.A. 81.7 N.A. 58.1 61.4 51 60.8
P-Site Identity: 100 100 N.A. 100 N.A. 100 66.6 N.A. N.A. 86.6 N.A. 80 N.A. 33.3 46.6 0 66.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 80 N.A. N.A. 100 N.A. 93.3 N.A. 73.3 86.6 20 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 28.7
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 45
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 0 0 0 0 0 0 0 50 0 9 % A
% Cys: 9 84 0 0 0 0 0 0 0 0 9 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 9 0 0 0 0 0 0 0 9 0 9 0 % E
% Phe: 0 0 0 0 0 0 84 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 9 0 0 0 0 0 9 0 0 17 % I
% Lys: 17 0 0 25 0 0 0 0 17 9 0 0 0 59 0 % K
% Leu: 9 0 0 0 0 34 0 0 0 0 0 9 0 0 59 % L
% Met: 0 0 0 0 0 25 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 9 0 0 0 0 0 0 0 0 9 0 0 % N
% Pro: 0 0 75 0 0 9 0 9 0 0 0 59 9 0 0 % P
% Gln: 9 0 0 0 0 0 0 0 9 0 0 17 0 9 0 % Q
% Arg: 42 9 0 59 84 0 0 0 67 75 0 0 0 25 0 % R
% Ser: 9 0 0 0 0 0 0 67 0 9 84 0 0 0 0 % S
% Thr: 9 0 0 0 9 0 9 25 9 9 0 0 17 0 0 % T
% Val: 0 0 17 0 9 25 0 0 0 0 9 0 0 0 17 % V
% Trp: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _