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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PNPLA6 All Species: 27.88
Human Site: T855 Identified Species: 55.76
UniProt: Q8IY17 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IY17 NP_006693.3 1366 149995 T855 D A S L T P W T V R C L R Q A
Chimpanzee Pan troglodytes XP_512331 1484 162976 T973 D A S L T P W T V R C L R Q A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_542111 1474 161798 L966 T P W T V R C L R Q A D C I L
Cat Felis silvestris
Mouse Mus musculus Q3TRM4 1355 149519 T844 D T S L T P W T V R C L R Q A
Rat Rattus norvegicus Q5BK26 1349 150006 T830 D S T L T P W T Q R C I R Q A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001106924 1321 147821 T832 D C T L T P W T V R C I R Q A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921208 1348 150755 T827 D S G M T P W T Q R C I R Q A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U969 1425 160554 M838 S A W T Q R C M R Q A D V I L
Honey Bee Apis mellifera XP_001120383 1324 149002 T806 D P T Y T L W T Q R C V R Q A
Nematode Worm Caenorhab. elegans Q02331 1353 152377 T807 D F T Q T N W T R R C L R Q A
Sea Urchin Strong. purpuratus XP_001202094 1454 161991 L911 I R Q A D C I L I V A L A D R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7S8J1 1515 167542 A994 V A I L P V T A G V P V V E F
Conservation
Percent
Protein Identity: 100 89 N.A. 88.1 N.A. 94.3 59.2 N.A. N.A. 77.1 N.A. 71.2 N.A. 40 45.2 33.1 43.9
Protein Similarity: 100 89.7 N.A. 90.2 N.A. 96.1 71.5 N.A. N.A. 84.7 N.A. 81.7 N.A. 58.1 61.4 51 60.8
P-Site Identity: 100 100 N.A. 0 N.A. 93.3 73.3 N.A. N.A. 80 N.A. 66.6 N.A. 6.6 60 66.6 6.6
P-Site Similarity: 100 100 N.A. 6.6 N.A. 93.3 93.3 N.A. N.A. 93.3 N.A. 86.6 N.A. 13.3 73.3 73.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 28.7
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 45
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 34 0 9 0 0 0 9 0 0 25 0 9 0 67 % A
% Cys: 0 9 0 0 0 9 17 0 0 0 67 0 9 0 0 % C
% Asp: 67 0 0 0 9 0 0 0 0 0 0 17 0 9 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 9 % F
% Gly: 0 0 9 0 0 0 0 0 9 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 9 0 0 0 9 0 9 0 0 25 0 17 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 50 0 9 0 17 0 0 0 42 0 0 17 % L
% Met: 0 0 0 9 0 0 0 9 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 17 0 0 9 50 0 0 0 0 9 0 0 0 0 % P
% Gln: 0 0 9 9 9 0 0 0 25 17 0 0 0 67 0 % Q
% Arg: 0 9 0 0 0 17 0 0 25 67 0 0 67 0 9 % R
% Ser: 9 17 25 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 9 9 34 17 67 0 9 67 0 0 0 0 0 0 0 % T
% Val: 9 0 0 0 9 9 0 0 34 17 0 17 17 0 0 % V
% Trp: 0 0 17 0 0 0 67 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _