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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PNPLA6 All Species: 26.36
Human Site: Y212 Identified Species: 52.73
UniProt: Q8IY17 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IY17 NP_006693.3 1366 149995 Y212 Q R L G Q G D Y V F R P G Q P
Chimpanzee Pan troglodytes XP_512331 1484 162976 Y330 Q R L G Q G D Y V F R P G Q P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_542111 1474 161798 Y332 Q R L S Q G D Y V F R P G Q P
Cat Felis silvestris
Mouse Mus musculus Q3TRM4 1355 149519 Y205 Q R L G Q G D Y V F R P G Q P
Rat Rattus norvegicus Q5BK26 1349 150006 H196 V Q L Q E G E H V F Q P G E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001106924 1321 147821 Y198 Q Q C Q Q G D Y V F R P G Q P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921208 1348 150755 Y196 L Q F Q Q G E Y V F R P G Q P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U969 1425 160554 Y200 L E L M A G D Y L F K I T D P
Honey Bee Apis mellifera XP_001120383 1324 149002 V176 F G H F E K P V F L K L C K H
Nematode Worm Caenorhab. elegans Q02331 1353 152377 R181 S K H G N S S R R R Q S T A F
Sea Urchin Strong. purpuratus XP_001202094 1454 161991 Y93 K F L P A G A Y L F Q R G Q P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7S8J1 1515 167542 L314 F Q Q S N D T L P S I P G T P
Conservation
Percent
Protein Identity: 100 89 N.A. 88.1 N.A. 94.3 59.2 N.A. N.A. 77.1 N.A. 71.2 N.A. 40 45.2 33.1 43.9
Protein Similarity: 100 89.7 N.A. 90.2 N.A. 96.1 71.5 N.A. N.A. 84.7 N.A. 81.7 N.A. 58.1 61.4 51 60.8
P-Site Identity: 100 100 N.A. 93.3 N.A. 100 46.6 N.A. N.A. 80 N.A. 66.6 N.A. 40 0 6.6 46.6
P-Site Similarity: 100 100 N.A. 93.3 N.A. 100 86.6 N.A. N.A. 86.6 N.A. 80 N.A. 53.3 20 20 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 28.7
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 45
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 20
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 17 0 9 0 0 0 0 0 0 9 0 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 0 0 0 0 0 9 50 0 0 0 0 0 0 9 0 % D
% Glu: 0 9 0 0 17 0 17 0 0 0 0 0 0 9 0 % E
% Phe: 17 9 9 9 0 0 0 0 9 75 0 0 0 0 9 % F
% Gly: 0 9 0 34 0 75 0 0 0 0 0 0 75 0 0 % G
% His: 0 0 17 0 0 0 0 9 0 0 0 0 0 0 9 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 9 9 0 0 0 % I
% Lys: 9 9 0 0 0 9 0 0 0 0 17 0 0 9 0 % K
% Leu: 17 0 59 0 0 0 0 9 17 9 0 9 0 0 0 % L
% Met: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 9 0 0 9 0 9 0 0 67 0 0 84 % P
% Gln: 42 34 9 25 50 0 0 0 0 0 25 0 0 59 0 % Q
% Arg: 0 34 0 0 0 0 0 9 9 9 50 9 0 0 0 % R
% Ser: 9 0 0 17 0 9 9 0 0 9 0 9 0 0 0 % S
% Thr: 0 0 0 0 0 0 9 0 0 0 0 0 17 9 0 % T
% Val: 9 0 0 0 0 0 0 9 59 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 67 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _